Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16628094 | 0.88 | CYP11B1 (0.45) | CYP11B1CYP11B2CASP3SENP8SENP7 | |
| SCHEMBL17954293 | 0.88 | CYP11B1 (0.45) | CYP11B1CYP11B2CASP3SENP8SENP7 | |
| SCHEMBL16624847 | 0.83 | CASP3 (0.50) | CYP11B1CYP11B2CASP3SENP8SENP7 | |
| SCHEMBL16624805 | 0.82 | ACSS2 (0.42) | CYP11B1CYP11B2CASP3SENP8SENP7 | |
| SCHEMBL17954315 | 0.82 | CASP3 (0.46) | CYP11B1CYP11B2CASP3SENP8SENP7 | |
| SCHEMBL17954297 | 0.82 | FYN (0.43) | CYP11B1CYP11B2RAB9AFFAR1KDM4E | |
| SCHEMBL20101406 | 0.81 | FFAR1 (0.41) | CYP11B1CYP11B2CASP3SENP8SENP7 | |
| SCHEMBL16627148 | 0.80 | FYN (0.39) | CYP11B1CYP11B2CASP3SENP8SENP7 | |
| SCHEMBL16624624 | 0.79 | CYP4F2 (0.42) | CYP11B1CYP11B2CASP3SENP8SENP7 | |
| SCHEMBL16631081 | 0.78 | FFAR1 (0.43) | CASP3SENP8SENP7SENP6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051045-A2 | 3'END CAPS FOR RNAi AGENTS FOR USE IN RNA INTERFERENCE | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |