SCHEMBL166311

SCHEMBL166311

O=C(O)c1cc(O)cs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL165499 0.78
SCHEMBL294584 0.78 CA12 (0.47)
SCHEMBL166310 0.75
SCHEMBL425130 0.75
SCHEMBL71474 0.75 DAO (0.58)
SCHEMBL6450949 0.74 ALAD (0.71)
SCHEMBL10125215 0.73
SCHEMBL3116336 0.73
Hydrochloric Acid SCHEMBL11059604 0.73 CES2 (0.67)
SCHEMBL788121 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7297168-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2007-11-20 US claimed
US-20050198745-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-09-15 US claimed
US-20250092067-A1 APT1 and APT2 Inhibitors and Uses Thereof CORNELL UNIVERSITY 2025-03-20 US disclosed
US-20240294499-A1 TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN CAPTOR THERAPEUTICS S.A. (PL) 2024-09-05 US disclosed
US-20230065745-A1 PIPERIDINE-2,6-DIONE DERIVATIVES WHICH BIND TO CEREBLON, AND METHODS OF USE THEREOF CAPTOR THERAPEUTICS S.A. (PL) 2023-03-02 US disclosed
WO-2022246115-A1 APT1 AND APT2 INHIBITORS AND USES THEREOF CORNELL UNIVERSITY (US) 2022-11-24 WO disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
WO-2021105335-A1 PIPERIDINE-2, 6-DIONE DERIVATIVES WHICH BIND TO CEREBLON, AND METHODS OF USE THEREOF CAPTOR THERAPEUTICS S.A. (PL) 2021-06-03 WO disclosed
US-10562844-B2 HYPDH inhibitors and methods of use for the treatment of kidney stones WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2020-02-18 US disclosed
US-10188910-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-01-29 US disclosed
US-20180126226-A1 GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2018-05-10 US disclosed
US-5112825-A Antirhinoviral heteroamine-substituted pyridazines JANSSEN PHARMACEUTICA N.V. (BE) 1992-05-12 US disclosed
EP-0211157-B1 ISOXAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHAMACEUTICAL COMPOSITIONS CONTAINING THEM Hafslund Nycomed Pharma Aktiengesellschaft (AT) 1991-01-02 EP disclosed
EP-0398427-A1 Antirhinoviral pyridazinamines JANSSEN PHARMACEUTICA N.V. (BE) 1990-11-22 EP disclosed
EP-0229660-B1 NITROGEN-CONTAINING ARYL METHOXYTHIOPHENE DERIVATIVES AND ACID ADDITION SALTS THEREOF, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM CL PHARMA AKTIENGESELLSCHAFT (AT) 1990-09-26 EP disclosed
US-4929534-A DEVELOPER RESISTANCE HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-29 US disclosed
US-4812472-A POLIO, AIDS CHEMIE LINZ AKTEINGESELLSCHAFT (AT) 1989-03-14 US disclosed
EP-0305873-A2 Positive photosensitive composition and photosensitive registration material made therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1989-03-08 EP disclosed
US-4778803-A Nitrogen-arylmethoxy-thiophene derivatives and acid addition salts thereof, and pharmaceutical preparations containing these compounds CHEMIE LINZ AKTIENGESELLSCHAFT (AT) 1988-10-18 US disclosed
EP-0229660-A2 Nitrogen-containing aryl methoxythiophene derivatives and acid addition salts thereof, process for their preparation and pharmaceutical compositions containing them CL PHARMA AKTIENGESELLSCHAFT (AT) 1987-07-22 EP disclosed