Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631763 | 0.86 | LMNA (0.34) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL16631754 | 0.84 | MEN1 (0.33) | LMNAKMT2AADORA2AADORA1MEN1 | |
| SCHEMBL18081799 | 0.81 | — | — | |
| SCHEMBL18080578 | 0.78 | ADORA2A (0.30) | ADORA2A | |
| SCHEMBL16631759 | 0.77 | KMT2A (0.32) | LMNAKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL16631757 | 0.74 | ADORA2A (0.46) | LMNAKMT2AADORA2AADORA1MEN1 | |
| SCHEMBL16631765 | 0.72 | NPSR1 (0.33) | ADORA2AADORA1KDM4EALDH1A1NPSR1 | |
| SCHEMBL16631362 | 0.72 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL18080576 | 0.69 | ADORA2A (0.31) | ADORA2A | |
| SCHEMBL16631612 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |