Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631764 | 0.84 | LMNA (0.33) | MEN1KMT2AADORA2AADORA1LMNA | |
| SCHEMBL18081779 | 0.81 | ADORA2A (0.32) | MEN1KMT2AADORA2AADORA1 | |
| SCHEMBL18080577 | 0.77 | ADORA2A (0.31) | ADORA2AADORA1 | |
| SCHEMBL16631757 | 0.75 | ADORA2A (0.46) | MEN1KMT2AADORA2AADORA1LMNA | |
| SCHEMBL16631759 | 0.75 | KMT2A (0.32) | MEN1KMT2ALMNAABCC4PKM | |
| SCHEMBL16631362 | 0.73 | KDM4E (0.33) | ALDH1A1KDM4E | |
| SCHEMBL18081974 | 0.71 | ADORA2A (0.33) | MEN1KMT2AADORA2AADORA1 | |
| SCHEMBL18080574 | 0.68 | ADORA2A (0.32) | ADORA2AADORA1 | |
| SCHEMBL16631765 | 0.68 | NPSR1 (0.33) | ADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL18081983 | 0.67 | ADORA2A (0.31) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |