Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631756 | 0.86 | ADORA1 (0.34) | ADORA1ADORA2A | |
| SCHEMBL16631759 | 0.77 | KMT2A (0.32) | NPSR1RXFP1ALDH1A1 | |
| SCHEMBL16631764 | 0.72 | LMNA (0.33) | NPSR1ADORA1ADORA2AKDM4EALDH1A1 | |
| SCHEMBL16631362 | 0.72 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL18081961 | 0.72 | ADORA1 (0.35) | ADORA1ADORA2A | |
| SCHEMBL16631928 | 0.70 | ADORA3 (0.31) | KDM4EALDH1A1 | |
| SCHEMBL16631754 | 0.68 | MEN1 (0.33) | ADORA1ADORA2AKDM4EALDH1A1 | |
| SCHEMBL16631927 | 0.66 | NSD2 (0.33) | — | |
| SCHEMBL18081978 | 0.65 | ADORA1 (0.49) | ADORA1ADORA2AKDM4EALDH1A1 | |
| SCHEMBL18080593 | 0.64 | KDM4E (0.38) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |