Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 19/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18081810 | 0.82 | DGAT1 (0.42) | DGAT1 | |
| SCHEMBL16631936 | 0.79 | HIF1A (0.33) | — | |
| SCHEMBL18080549 | 0.79 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL16631430 | 0.75 | KDM4E (0.36) | DGAT1 | |
| SCHEMBL16631478 | 0.74 | HCAR2 (0.34) | — | |
| SCHEMBL16631493 | 0.71 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL16631394 | 0.70 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL16631930 | 0.69 | HCAR2 (0.31) | — | |
| SCHEMBL16631883 | 0.68 | PYGL (0.39) | DGAT1 | |
| SCHEMBL18080552 | 0.68 | DGAT1 (0.34) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |