Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18081973 | 0.82 | PDE3B (0.32) | PDE3BPDE3AAR | |
| SCHEMBL18080551 | 0.79 | PDE2A (0.31) | PDE3BPDE3APTGES | |
| SCHEMBL16631930 | 0.75 | HCAR2 (0.31) | HCAR2 | |
| SCHEMBL16631474 | 0.74 | DGAT1 (0.41) | — | |
| SCHEMBL16631745 | 0.74 | HCAR2 (0.34) | HCAR2PDE3BPDE3AAR | |
| SCHEMBL16631475 | 0.71 | — | — | |
| SCHEMBL16631430 | 0.70 | KDM4E (0.36) | HCAR2AR | |
| SCHEMBL16631477 | 0.69 | PDE3B (0.33) | PDE3BPDE3AAR | |
| SCHEMBL18080224 | 0.68 | KDM4E (0.39) | — | |
| SCHEMBL18080554 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |