Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631938 | 0.84 | KMT2A (0.36) | MAPTKMT2ARXFP1KDM4EALDH1A1 | |
| SCHEMBL16631930 | 0.83 | HCAR2 (0.31) | — | |
| SCHEMBL18081976 | 0.81 | OPRK1 (0.32) | KMT2AKDM4E | |
| SCHEMBL16631707 | 0.75 | KMT2A (0.31) | MAPTKMT2ARXFP1 | |
| SCHEMBL16631705 | 0.74 | TNKS (0.33) | MAPTKDM4EALDH1A1 | |
| SCHEMBL16631937 | 0.74 | KDM4E (0.37) | MAPTKMT2ARXFP1KDM4EALDH1A1 | |
| SCHEMBL18081955 | 0.71 | PARP1 (0.30) | — | |
| SCHEMBL16631452 | 0.69 | L3MBTL1 (0.33) | MAPTKMT2ARXFP1KDM4E | |
| SCHEMBL16631929 | 0.68 | OPRK1 (0.32) | KMT2AKDM4E | |
| SCHEMBL16631299 | 0.67 | KDM4E (0.40) | MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |