Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 3/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16632850 | 1.00 | KDM4E (0.52) | KDM4EALDH1A1POLBL3MBTL1LMNA | |
| SCHEMBL5848689 | 0.77 | KDM4E (0.66) | KDM4EALDH1A1LMNAAPPPTGER1 | |
| SCHEMBL5848694 | 0.77 | KDM4E (0.66) | KDM4EALDH1A1LMNAAPPPTGER1 | |
| SCHEMBL5839199 | 0.77 | FOLH1 (0.56) | KDM4EALDH1A1POLBL3MBTL1FOLH1 | |
| SCHEMBL31528260 | 0.76 | RAB9A (0.46) | KDM4EALDH1A1POLBL3MBTL1LMNA | |
| SCHEMBL16645304 | 0.76 | CNR2 (0.43) | KDM4EALDH1A1POLBL3MBTL1LMNA | |
| SCHEMBL9756730 | 0.76 | FOLH1 (0.49) | KDM4EALDH1A1POLBL3MBTL1FOLH1 | |
| SCHEMBL6762318 | 0.76 | CTSV (0.52) | LMNAFOLH1PTGER1 | |
| SCHEMBL31528273 | 0.76 | LIPE (0.53) | KDM4EALDH1A1POLBL3MBTL1LMNA | |
| SCHEMBL28157939 | 0.76 | APP (0.60) | KDM4EALDH1A1POLBL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902986-B2 | Enterobactin conjugates and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-02-27 | — | — | US | disclosed |
| US-20150105337-A1 | ENTEROBACTIN CONJUGATES AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105337-A1 | ENTEROBACTIN CONJUGATES AND USES THEREOF | BTD, VIP, SLC10A2 | KDM4E 3816/4885ALDH1A1 2901/4885POLB 2130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.