Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756722 | 0.87 | LMNA (0.52) | L3MBTL1ALDH1A1MEN1KMT2APTPN1 | |
| SCHEMBL9756728 | 0.87 | SGMS2 (0.43) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5839199 | 0.79 | FOLH1 (0.56) | FOLH1MCL1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL16632852 | 0.76 | KDM4E (0.52) | FOLH1MCL1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL16632850 | 0.76 | KDM4E (0.52) | FOLH1MCL1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL2743027 | 0.76 | ATM (0.51) | L3MBTL1ALDH1A1POLBKMT2AMAPT | |
| SCHEMBL4301163 | 0.76 | FOLH1 (0.55) | FOLH1MCL1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL3102000 | 0.75 | ATM (0.50) | L3MBTL1ALDH1A1POLBKMT2AMAPT | |
| SCHEMBL1305739 | 0.75 | PTGER1 (0.61) | FOLH1MCL1L3MBTL1ALDH1A1PTGER1 | |
| SCHEMBL6762318 | 0.75 | CTSV (0.52) | FOLH1PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077432-A | Monobactam hydrazides containing catechol sulfonic acid groups | E. R. SQUIBB & SONS, INC. (US) | 1991-12-31 | — | — | US | disclosed |
| EP-0438752-A1 | Monobactam hydrazides containing catechol sulfonic acid groups | E.R. SQUIBB & SONS, INC. (US) | 1991-07-31 | — | — | EP | disclosed |
| US-5030724-A | Monobactam hydrazides containing catechol sulfonic acid groups | E. R. SQUIBB & SONS, INC. (US) | 1991-07-09 | — | — | US | disclosed |