Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.43 |
| ▸ | SLC2A3 | P11169 | 3/20 | 0.43 |
| ▸ | KIT | P10721 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15326101 | 0.95 | HTR7 (0.43) | MEN1CYP1A2CYP3A4KMT2ACYP2D6 | |
| SCHEMBL15326102 | 0.84 | HTR7 (0.41) | MEN1CYP1A2CYP3A4KMT2ASLC2A1 | |
| SCHEMBL15326093 | 0.81 | DRD2 (0.52) | HTR7DRD2DRD3HTR1AHTR2A | |
| SCHEMBL16633179 | 0.79 | MEN1 (0.45) | MEN1CYP1A2CYP3A4KMT2ACYP2D6 | |
| SCHEMBL27940453 | 0.77 | DRD2 (0.56) | HTR7DRD2DRD3HTR1AALDH1A1 | |
| SCHEMBL6995702 | 0.76 | HTR7 (0.44) | MEN1CYP1A2CYP3A4KMT2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL7943961 | 0.75 | HTR7 (0.43) | MEN1CYP1A2CYP3A4KMT2ACYP2D6 | |
| SCHEMBL15326104 | 0.75 | DRD2 (0.54) | HTR7DRD2DRD3HTR1AHTR2A | |
| SCHEMBL6999464 | 0.75 | HTR7 (0.41) | MEN1CYP1A2CYP3A4KMT2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL6990810 | 0.74 | SLC2A1 (0.41) | MEN1CYP1A2CYP3A4KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238632-B2 | 3-cyanoanilinoalkylarylpiperazine derivative and use thereof in preparing drugs | NHWA Pharma, Corporation (CN) | 2016-01-19 | — | — | US | claimed |
| US-20150105399-A1 | 3-CYANOANILINOALKYLARYLPIPERAZINE DERIVATIVE AND USE THEREOF IN PREPARING DRUGS | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2015-04-16 | — | — | US | claimed |
| CN-103360342-A | 3-Cyanoaniline alkyl aryl piperazine derivative and application in preparing medicaments | JIANGSU NHWA PHARMACEUTICAL CO LTD | 2013-10-23 | — | — | CN | claimed |
| US-9238632-B2 | 3-cyanoanilinoalkylarylpiperazine derivative and use thereof in preparing drugs | NHWA Pharma, Corporation (CN) | 2016-01-19 | — | — | US | disclosed |
| US-20150105399-A1 | 3-CYANOANILINOALKYLARYLPIPERAZINE DERIVATIVE AND USE THEREOF IN PREPARING DRUGS | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2015-04-16 | — | — | US | disclosed |
| CN-103360342-A | 3-Cyanoaniline alkyl aryl piperazine derivative and application in preparing medicaments | JIANGSU NHWA PHARMACEUTICAL CO LTD | 2013-10-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105399-A1 | 3-CYANOANILINOALKYLARYLPIPERAZINE DERIVATIVE AND USE THEREOF IN PREPARING DRUGS | HTR5A, HTR3C, HTR3A | MEN1 4735/4885CYP1A2 187/4885CYP3A4 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.