Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | TNK1 | Q13470 | 3/20 | 0.37 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634668 | 0.88 | KMT2A (0.45) | CREBBPEP300MEN1KMT2ARORC | |
| SCHEMBL3811958 | 0.73 | KMT2A (0.64) | CREBBPEP300MEN1KMT2AALDH1A1 | |
| SCHEMBL16634747 | 0.73 | CREBBP (0.46) | CREBBPEP300MEN1KMT2ARORC | |
| SCHEMBL16634626 | 0.70 | HSP90AA1 (0.54) | PARP1RORCAURKASMN1; SMN2KDM4E | |
| SCHEMBL4505041 | 0.70 | MEN1 (0.54) | CREBBPEP300MEN1KMT2AALDH1A1 | |
| SCHEMBL16634625 | 0.70 | HCAR3 (0.52) | CREBBPEP300MEN1KMT2AALDH1A1 | |
| SCHEMBL16634623 | 0.70 | HCAR3 (0.52) | CREBBPEP300MEN1KMT2AALDH1A1 | |
| SCHEMBL2881940 | 0.70 | MEN1 (0.44) | CREBBPEP300MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16634859 | 0.69 | AURKA (0.44) | MEN1KMT2AAURKASMN1; SMN2KDM4E | |
| SCHEMBL20847149 | 0.69 | HPGD (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015052675-A1 | SUBSTITUTED DIHYDRO-BENZIMIDAZOLE COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-04-16 | — | — | WO | disclosed |