Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 3/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL699273 | 0.80 | LMNA (0.65) | AURKADAOHSP90AA1LMNAMEN1 | |
| SCHEMBL29367625 | 0.80 | LMNA (0.65) | AURKADAOHSP90AA1LMNAMEN1 | |
| SCHEMBL21463671 | 0.78 | DAO (0.50) | AURKADAOHSP90AA1LMNAMEN1 | |
| SCHEMBL4098385 | 0.78 | AURKA (0.56) | AURKADAOHSP90AA1LMNAMEN1 | |
| SCHEMBL9994946 | 0.78 | HTT (0.56) | AURKADAOHSP90AA1LMNAMEN1 | |
| SCHEMBL23119669 | 0.78 | LMNA (0.67) | AURKADAOHSP90AA1LMNAMEN1 | |
| SCHEMBL8156714 | 0.78 | GABRP (0.52) | AURKADAOHSP90AA1LMNAMEN1 | |
| SCHEMBL31609285 | 0.77 | L3MBTL1 (0.55) | LMNAKMT2AL3MBTL1MAPTKDM4E | |
| SCHEMBL16634744 | 0.77 | L3MBTL1 (0.55) | AURKADAOHSP90AA1LMNAMEN1 | |
| SCHEMBL29092672 | 0.76 | SMN1; SMN2 (0.51) | AURKADAOHSP90AA1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015052675-A1 | SUBSTITUTED DIHYDRO-BENZIMIDAZOLE COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-04-16 | — | — | WO | disclosed |