Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | FADS1 | O60427 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1584087 | 0.99 | ADRB1 (0.57) | ADRB1MAPTALOX5MGLLSLC6A2 | |
| SCHEMBL1665546 | 0.83 | ADRB1 (0.56) | ADRB1MAPTMGLLSLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL1584077 | 0.82 | ADRB1 (0.54) | ADRB1MAPTMGLLSLC6A2SLC6A4 | |
| SCHEMBL12892216 | 0.82 | ADRB1 (0.57) | ADRB1MAPTALOX5MGLLSLC6A2 | |
| SCHEMBL31471960 | 0.82 | DRD2 (0.46) | SLC6A2SLC6A4SLC6A3DRD2DRD3 | |
| SCHEMBL25366082 | 0.81 | ALOX5 (0.55) | ADRB1MAPTALOX5MGLLDRD2 | |
| SCHEMBL30516650 | 0.81 | ALOX5 (0.55) | ADRB1MAPTALOX5MGLLDRD2 | |
| Hydrochloric Acid SCHEMBL6393637 | 0.81 | DRD2 (0.46) | MAPTSLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL1583660 | 0.80 | POLB (0.49) | MAPTALOX5MGLLSLC6A2SLC6A4 | |
| SCHEMBL5604528 | 0.80 | ADRB1 (0.55) | ADRB1MAPTALOX5MGLLDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |