Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | CTSG | P08311 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25366082 | 1.00 | ALOX5 (0.55) | ALOX5MGLLMAPTADRB1DRD2 | |
| SCHEMBL11116125 | 0.92 | NPC1 (0.60) | ALOX5MGLLDRD2DRD3NPC1 | |
| SCHEMBL21504279 | 0.90 | NPC1 (0.56) | ALOX5MGLLMAPTDRD2DRD3 | |
| SCHEMBL25079569 | 0.82 | DDB1 (0.66) | ALOX5MGLLMAPTADRB1DRD2 | |
| SCHEMBL2046118 | 0.81 | POLB (0.61) | MGLLMAPTADRB1NPC1RAB9A | |
| SCHEMBL1663489 | 0.81 | ADRB1 (0.59) | ALOX5MGLLMAPTADRB1DRD2 | |
| SCHEMBL5736692 | 0.81 | CTSG (0.51) | MGLLNPC1RAB9ACTSGCMA1 | |
| SCHEMBL9564052 | 0.80 | L3MBTL1 (0.62) | ALOX5MGLLMAPTADRB1DRD2 | |
| Hydrochloric Acid SCHEMBL1584087 | 0.80 | ADRB1 (0.57) | ALOX5MGLLMAPTADRB1DRD2 | |
| SCHEMBL26784122 | 0.79 | FFAR4 (0.42) | ALOX5MAPTCYP11B1CYP11B2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013017-A | Pharmaceutical composition for treating cancer comprising an anticancer agent and a novel compound having an inhibitory activity on prostaglandin E2 receptor | 治纳辅医药科技有限公司 | 2024-11-22 | — | — | CN | disclosed |
| WO-2023158221-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING CANCER, COMPRISING ANTICANCER AGENT AND NOVEL COMPOUND HAVING INHIBITORY ACTIVITY WITH RESPECT TO PROSTAGLANDIN E2 RECEPTORS | 주식회사 카나프테라퓨틱스 | 2023-08-24 | — | — | WO | disclosed |
| CN-116529238-A | Novel prostaglandin E 2 Compounds with receptor inhibiting activity and uses thereof | 治纳辅医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |