Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663198 | 0.83 | CYP3A4 (0.35) | EGFRMAPT | |
| SCHEMBL1666489 | 0.77 | MAPT (0.36) | EGFRMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL25934717 | 0.68 | MMP2 (0.35) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL5238331 | 0.67 | HTR2A (0.33) | MAPT | |
| SCHEMBL8817941 | 0.66 | NOTUM (0.39) | ALDH1A1 | |
| SCHEMBL1662907 | 0.66 | ALDH1A1 (0.48) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL1664597 | 0.65 | ALDH1A1 (0.43) | EGFRMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL10073218 | 0.64 | CYP3A4 (0.49) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL1663125 | 0.63 | ALDH1A1 (0.40) | EGFRMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL5198243 | 0.62 | HSD11B1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |