Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 4/20 | 0.34 |
| ▸ | PLAU | P00749 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663198 | 0.84 | CYP3A4 (0.35) | MAPTKDM4EEGFRBACE1CA12 | |
| SCHEMBL1663543 | 0.77 | EGFR (0.31) | MAPTEGFRALDH1A1MEN1KMT2A | |
| SCHEMBL1664651 | 0.72 | ALDH1A1 (0.44) | MAPTKDM4EEGFRELANEPLAU | |
| SCHEMBL25934717 | 0.72 | MMP2 (0.35) | MAPTKDM4EBACE1ALDH1A1MEN1 | |
| SCHEMBL5470124 | 0.70 | BACE1 (0.46) | MAPTKDM4EBACE1CA12CA1 | |
| SCHEMBL8260068 | 0.69 | MRGPRX4 (0.51) | MAPTBACE1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5471856 | 0.68 | BACE1 (0.44) | MAPTKDM4EBACE1ALDH1A1CYP3A4 | |
| SCHEMBL28371702 | 0.67 | TLR8 (0.42) | MAPTKDM4ECA12CA1CA2 | |
| SCHEMBL8320447 | 0.65 | LOXL2 (0.56) | MAPTKDM4EALDH1A1NPSR1HPGD | |
| SCHEMBL25372714 | 0.65 | ALDH1A1 (0.45) | MAPTKDM4EELANEPLAUF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |