Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666489 | 0.84 | MAPT (0.36) | CYP3A4EGFRKDM4EMAPTBACE1 | |
| SCHEMBL1663543 | 0.83 | EGFR (0.31) | EGFRMAPT | |
| SCHEMBL25934717 | 0.74 | MMP2 (0.35) | KDM4EMAPTBACE1 | |
| SCHEMBL1664597 | 0.73 | ALDH1A1 (0.43) | CYP3A4ACHEEGFRKDM4EMAPT | |
| SCHEMBL17918565 | 0.66 | AR (0.35) | CYP3A4KDM4EMAPTBACE1CA12 | |
| SCHEMBL5462929 | 0.65 | EGFR (0.39) | CYP3A4ACHEEGFRMAPTBACE1 | |
| SCHEMBL2220207 | 0.65 | MRGPRX4 (0.51) | KDM4EMAPTBACE1 | |
| SCHEMBL21957858 | 0.65 | L3MBTL1 (0.37) | KDM4EMAPTBACE1 | |
| SCHEMBL1663399 | 0.65 | ELANE (0.40) | CYP3A4EGFRKDM4EMAPT | |
| SCHEMBL28371702 | 0.65 | TLR8 (0.42) | KDM4EMAPTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |