Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086686 | 1.00 | LPAR1 (0.56) | LPAR1 | |
| SCHEMBL24625000 | 0.97 | LPAR1 (0.53) | LPAR1 | |
| SCHEMBL5936343 | 0.93 | LPAR1 (0.51) | LPAR1 | |
| SCHEMBL8277024 | 0.93 | LPAR1 (0.51) | LPAR1 | |
| SCHEMBL31520002 | 0.93 | LPAR1 (0.51) | LPAR1 | |
| SCHEMBL6805094 | 0.93 | LPAR1 (0.51) | LPAR1 | |
| SCHEMBL9905957 | 0.91 | LPAR1 (0.47) | LPAR1 | |
| SCHEMBL10597149 | 0.90 | ALDH1A1 (0.56) | — | |
| SCHEMBL9905966 | 0.90 | ALDH1A1 (0.56) | — | |
| SCHEMBL16140067 | 0.90 | ALDH1A1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3065732-A1 | COMPOUNDS, COMPOSITIONS AND USES THEREOF FOR THE PREVENTION AND/OR TREATMENT OF DYSLIPIDEMIA | Centre National de la Recherche Scientifique (CNRS) (FR) | 2016-09-14 | — | — | EP | claimed |
| WO-2015052237-A1 | COMPOUNDS, COMPOSITIONS AND USES THEREOF FOR THE PREVENTION AND/OR TREATMENT OF DYSLIPIDEMIA | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2015-04-16 | — | — | WO | claimed |
| CN-105744934-B | Composition for preventing or treating the compound of dyslipidemia and comprising this kind of compound | 法国国家科学研究中心 | 2019-08-20 | — | — | CN | disclosed |
| US-10231985-B2 | Compounds and compositions comprising such compounds for the prevention or treatment of dyslipidaemias | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2019-03-19 | — | — | US | disclosed |
| US-10231985-B2 | Compounds and compositions comprising such compounds for the prevention or treatment of dyslipidaemias | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2019-03-19 | — | — | US | disclosed |
| US-9821000-B2 | Compounds, compositions and corresponding uses for preventing and/or treating of dyslipidemia | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2017-11-21 | — | — | US | disclosed |
| US-9821000-B2 | Compounds, compositions and corresponding uses for preventing and/or treating of dyslipidemia | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2017-11-21 | — | — | US | disclosed |
| US-20160287542-A1 | COMPOUNDS, COMPOSITIONS AND CORRESPONDING USES FOR PREVENTING AND/OR TREATING OF DYSLIPIDEMIA | UNIVERSITE DE POITIERS (FR) | 2016-10-06 | — | — | US | disclosed |
| US-20160287542-A1 | COMPOUNDS, COMPOSITIONS AND CORRESPONDING USES FOR PREVENTING AND/OR TREATING OF DYSLIPIDEMIA | UNIVERSITE DE POITIERS (FR) | 2016-10-06 | — | — | US | disclosed |
| EP-3065732-A1 | COMPOUNDS, COMPOSITIONS AND USES THEREOF FOR THE PREVENTION AND/OR TREATMENT OF DYSLIPIDEMIA | Centre National de la Recherche Scientifique (CNRS) (FR) | 2016-09-14 | — | — | EP | disclosed |
| EP-3065733-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING SUCH COMPOUNDS FOR THE PREVENTION OR TREATMENT OF DYSLIPIDAEMIAS | Centre National De La Recherche Scientifique (FR) | 2016-09-14 | — | — | EP | disclosed |
| US-20160256429-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING SUCH COMPOUNDS FOR THE PREVENTION OR TREATMENT OF DYSLIPIDAEMIAS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2016-09-08 | — | — | US | disclosed |
| US-20160256429-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING SUCH COMPOUNDS FOR THE PREVENTION OR TREATMENT OF DYSLIPIDAEMIAS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2016-09-08 | — | — | US | disclosed |
| US-20150321992-A1 | TRIACYLGLYCEROL OLIGOMERS | TRENT UNIVERSITY (CA) | 2015-11-12 | — | — | US | disclosed |
| WO-2015052237-A1 | COMPOUNDS, COMPOSITIONS AND USES THEREOF FOR THE PREVENTION AND/OR TREATMENT OF DYSLIPIDEMIA | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2015-04-16 | — | — | WO | disclosed |
| WO-2015052433-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING SUCH COMPOUNDS FOR THE PREVENTION OR TREATMENT OF DYSLIPIDAEMIAS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160287542-A1 | COMPOUNDS, COMPOSITIONS AND CORRESPONDING USES FOR PREVENTING AND/OR TREATING OF DYSLIPIDEMIA | LIPC, CPT1A, LIPA | LPAR1 103/4885 |
| US-20160256429-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING SUCH COMPOUNDS FOR THE PREVENTION OR TREATMENT OF DYSLIPIDAEMIAS | LIPC, FABP4, PNLIP | LPAR1 224/4885 |
| US-20150321992-A1 | TRIACYLGLYCEROL OLIGOMERS | SQLE, DGAT2, PNLIP | LPAR1 198/4885 |
| US-10231985-B2 | Compounds and compositions comprising such compounds for the prevention or treatment of dyslipidaemias | LIPC, FABP4, PNLIP | LPAR1 224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.