Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16324730 | 0.81 | RAB9A (0.40) | POLBL3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL16637430 | 0.79 | OPRM1 (0.44) | NSD2OPRM1OPRL1L3MBTL1SMN1; SMN2 | |
| SCHEMBL16637299 | 0.75 | POLB (0.45) | CYP11B2ELANEPOLBNSD2OPRM1 | |
| SCHEMBL16430910 | 0.69 | ACACA (0.48) | CYP11B2ELANEPOLBOPRM1OPRL1 | |
| SCHEMBL21753280 | 0.64 | ACACA (0.56) | POLBKCNJ1CYP2D6ACACATSHR | |
| SCHEMBL6740517 | 0.64 | POLB (0.46) | CYP11B2ELANEPOLBOPRM1OPRL1 | |
| SCHEMBL21764939 | 0.64 | USP2 (0.43) | ELANEPOLBOPRM1OPRL1PGR | |
| SCHEMBL7422542 | 0.63 | POLB (0.49) | CYP11B2ELANEPOLB | |
| Hydrochloric Acid SCHEMBL21753301 | 0.63 | USP2 (0.42) | ELANEPOLBOPRM1OPRL1PGR | |
| SCHEMBL23299517 | 0.63 | GRM2 (0.43) | CYP11B2ELANEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051713-A1 | 4,5-DIHYDRO-PYRAZOLO[3,4-C]PYRIDIN-2-ONE SPIRO DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2015-04-16 | — | — | WO | disclosed |
| WO-2015051713-A1 | 4,5-DIHYDRO-PYRAZOLO[3,4-C]PYRIDIN-2-ONE SPIRO DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2015-04-16 | — | — | WO | disclosed |