SCHEMBL16640698

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15358687	0.93	MAPT (0.50)	MAPTGAAGFERRAD52KDM4E
	SCHEMBL17265651	0.90	MAPT (0.51)	MAPTGAAGFERRAD52KDM4E
	SCHEMBL17264115	0.90	ALDH1A1 (0.46)	MAPTGAAGFERRAD52KDM4E
	SCHEMBL17265653	0.82	MAPT (0.54)	MAPTGAAGFERRAD52KDM4E
	SCHEMBL17264113	0.80	ALDH1A1 (0.48)	MAPTGAAGFERRAD52KDM4E
	SCHEMBL30730933	0.78	KDM4E (0.42)	MAPTRAD52KDM4EALDH1A1HTT
	SCHEMBL30879098	0.77	MAPT (0.61)	MAPTGAAGFERRAD52KDM4E
	SCHEMBL12006141	0.77	MAPT (0.61)	MAPTGAAGFERRAD52KDM4E
	SCHEMBL188609	0.76	MAPT (0.56)	MAPTGAAGFERRAD52KDM4E
	SCHEMBL11347930	0.76	TYR (0.47)	MAPTGAAMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.