Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.39 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16644673 | 0.82 | CYP1A2 (0.40) | CYP1A2CYP2C9CYP2C19L3MBTL1MAPT | |
| SCHEMBL16632385 | 0.82 | L3MBTL1 (0.44) | L3MBTL1MAPTTDP1MAPK1SMN1; SMN2 | |
| SCHEMBL16632579 | 0.77 | L3MBTL1 (0.41) | L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL837183 | 0.76 | BCHE (0.50) | CYP1A2CYP2C9CYP2C19L3MBTL1PDE5A | |
| SCHEMBL10730442 | 0.75 | CYP1A2 (0.64) | CYP1A2CYP2C9CYP2C19L3MBTL1MAPT | |
| SCHEMBL8578238 | 0.70 | ACHE (0.45) | MAPK1TLR8CYP3A4 | |
| 1,2-Dibutoxybenzene SCHEMBL1226749 | 0.70 | CYP1A2 (0.72) | CYP1A2CYP2C9CYP2C19L3MBTL1MAPT | |
| 1,2-Dibutoxybenzene SCHEMBL29428927 | 0.70 | CYP1A2 (0.72) | CYP1A2CYP2C9CYP2C19L3MBTL1MAPT | |
| SCHEMBL6933945 | 0.69 | LMNA (0.57) | CYP1A2CYP2C9CYP2C19L3MBTL1MAPT | |
| SCHEMBL16644669 | 0.68 | HPGD (0.49) | CYP1A2CYP2C9CYP2C19L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382245-B2 | Compounds and methods for treating HIV infections | YALE UNIVERSITY (US) | 2016-07-05 | — | — | US | disclosed |
| US-20150105351-A1 | COMPOUNDS AND METHODS FOR TREATING HIV INFECTIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105351-A1 | COMPOUNDS AND METHODS FOR TREATING HIV INFECTIONS | POLM, POLRMT, DHFR | CYP1A2 567/4885CYP2C9 1797/4885CYP2C19 1318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.