SCHEMBL1664508

SCHEMBL1664508

CCC([SiH3])(CC)CCCN

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 9/20 0.35
TSHR P16473 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 1/20 0.35
EPHX1 P07099 1/20 0.35
NFKB1 P19838 1/20 0.32
FDPS P14324 1/20 0.31
PDE3A Q14432 1/20 0.31
KIF11 P52732 2/20 0.31
CA12 O43570 2/20 0.30
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA3 P07451 2/20 0.30
CA4 P22748 2/20 0.30
CA6 P23280 2/20 0.30
CA5A P35218 2/20 0.30
CA7 P43166 2/20 0.30
CA9 Q16790 2/20 0.30
CA14 Q9ULX7 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21748448 0.82 NFKB1 (0.40) DNM1TSHRNFKB1FDPSPDE3A
SCHEMBL23923658 0.77 NFKB1 (0.44) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL21748452 0.71 DNM1 (0.50) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL8744280 0.71 DNM1 (0.38) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL23923946 0.71 DNM1 (0.50) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL15534110 0.69
SCHEMBL9313097 0.69 DNM1 (0.36) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL5706629 0.69
SCHEMBL20387125 0.69 DNM1 (0.36) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL6203864 0.69 DNM1 (0.36) DNM1TSHRMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2771379-A2 POLYMER, COMPOSITIONS AND PROCESS FOR PREPARING THEM DSM IP Assets B.V. (NL) 2014-09-03 EP claimed
US-20140242399-A1 POLYMER, COMPOSITIONS AND PROCESS FOR PREPARING THEM DSM IP ASSETS B.V. (NL) 2014-08-28 US claimed
WO-2013060767-A2 POLYMER, COMPOSITIONS AND PROCESS FOR PREPARING THEM DSM IP ASSETS B.V. (NL) 2013-05-02 WO claimed
US-12594700-B2 Coatings from polyisocyanurate coatings (rim) and their use in injection molding processes COVESTRO DEUTSCHLAND AG (DE) 2026-04-07 US disclosed
EP-4606829-A1 PROCESS FOR THE PREPARATION OF ALKOXYSILANE-FUNCTIONAL POLYURETHANES AND POLYURETHANE UREAS Covestro Deutschland AG (DE) 2025-08-27 EP disclosed
US-12331214-B2 Resistant 2K-PUR coatings COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2025-06-17 US disclosed
EP-3994192-B1 RESISTANT 2K-PUR COATINGS COVESTRO DEUTSCHLAND AG (DE) 2025-04-30 EP disclosed
US-20250043146-A1 MULTILAYER CONSTRUCTION ON METAL SUBSTRATES BASED ON POLYASPARTATE COATINGS COVESTRO DEUTSCHLAND AG (DE) 2025-02-06 US disclosed
EP-4453107-A1 MULTILAYER CONSTRUCTION ON METAL SUBSTRATES BASED ON POLYASPARATE COATINGS Covestro Deutschland AG (DE) 2024-10-30 EP disclosed
US-20240294798-A1 Coating Agents and Coatings That Are Obtainable Therefrom and Have Improved Resistance to Soiling and (Self-) Cleaning Properties COVESTRO DEUTSCHLAND AG (DE) 2024-09-05 US disclosed
EP-4359459-A1 COATING AGENTS AND COATINGS THAT ARE OBTAINABLE THEREFROM AND HAVE IMPROVED RESISTANCE TO SOILING AND (SELF-)CLEANING PROPERTIES Covestro Deutschland AG (DE) 2024-05-01 EP disclosed
US-4933244-A Phenolic epoxy polymer or polyester and charge transporting small molecule at interface between a charge generator layer and a charge transport layer XEROX CORPORATION (US) 1990-06-12 US disclosed
US-4664995-A Electrostatographic imaging members XEROX CORPORATION (US) 1987-05-12 US disclosed
US-4654284-A AMINOSILANE, SILICA XEROX CORPORATION (US) 1987-03-31 US disclosed
EP-0213723-A2 Photoreceptor XEROX CORPORATION (US) 1987-03-11 EP disclosed
US-4639402-A LESSENED DARK DECAY, XEROGRAPHY XEROX CORPORATION (US) 1987-01-27 US disclosed
US-4634756-A SILOXANE THIN FILM ON DIELECTRIC SUBSTRATE XEROX CORPORATION (US) 1987-01-06 US disclosed
EP-0072473-B1 ORGANOSILICONE COATING COMPOSITION Treadway, Gerald D. (US) 1986-02-05 EP disclosed
US-4378250-A POLYSILOXANES TREADWAY GERALD D (US) 1983-03-29 US disclosed
EP-0072473-A2 Organosilicone coating composition Treadway, Gerald D. (US) 1983-02-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12594700-B2 Coatings from polyisocyanurate coatings (rim) and their use in injection molding processes TST, C9, ESD DNM1 4874/4885TSHR 3835/4885MEN1 1073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.