Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ESRRB | O95718 | 2/20 | 0.42 |
| ▸ | ESRRA | P11474 | 2/20 | 0.42 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27674777 | 0.83 | CYP17A1 (0.42) | RORCCYP17A1CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL15646152 | 0.81 | SMN1; SMN2 (0.48) | RORCKMT2ADYRK1A | |
| SCHEMBL27674700 | 0.81 | ESR2 (0.47) | CYP17A1CYP3A4CYP11B1CYP11B2ESR2 | |
| SCHEMBL15646666 | 0.80 | MAOA (0.52) | RORCCYP3A4ADORA2A | |
| SCHEMBL27693036 | 0.79 | CYP17A1 (0.39) | CYP17A1CYP3A4CYP11B1CYP11B2ESR2 | |
| SCHEMBL27674776 | 0.79 | ESR2 (0.42) | CYP17A1CYP3A4CYP11B1CYP11B2ESR2 | |
| SCHEMBL5653842 | 0.76 | PIK3CA (0.62) | ALOX5ESR2ESR1KMT2APELI1 | |
| SCHEMBL23674185 | 0.74 | ESR2 (0.56) | CYP17A1CYP3A4CYP11B1CYP11B2ALOX5 | |
| SCHEMBL16585910 | 0.74 | PIK3CA (0.60) | ALOX5ESR2ESR1KMT2APELI1 | |
| SCHEMBL30120338 | 0.73 | ESR2 (0.42) | CYP17A1CYP3A4CYP11B1CYP11B2ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150105404-A1 | PHENYL LINKED QUINOLINYL MODULATORS OF RORyt | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105404-A1 | PHENYL LINKED QUINOLINYL MODULATORS OF RORyt | RORC, RORA, RORB | RORC 1/4885CYP17A1 418/4885CYP3A4 1047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.