Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.31 |
| ▸ | GABRE | P78334 | 2/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.31 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.31 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.31 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15691923 | 0.87 | LMNA (0.30) | ALDH1A1LMNASLC15A2TDP1 | |
| SCHEMBL25641491 | 0.83 | ALDH1A1 (0.36) | ALDH1A1LMNASLC15A2TDP1 | |
| SCHEMBL18494808 | 0.81 | ALDH1A1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL19456824 | 0.78 | ALDH1A1 (0.39) | ALDH1A1LMNASLC15A2TDP1 | |
| SCHEMBL19456825 | 0.78 | ALDH1A1 (0.39) | ALDH1A1LMNASLC15A2TDP1 | |
| SCHEMBL25641496 | 0.78 | ALDH1A1 (0.39) | ALDH1A1LMNASLC15A2TDP1 | |
| SCHEMBL16643860 | 0.78 | TSHR (0.31) | LMNATSHRGABRPGABRDGABRA1 | |
| SCHEMBL29282934 | 0.78 | FOLH1 (0.48) | ALDH1A1LMNATSHRGABRPGABRD | |
| SCHEMBL19522729 | 0.75 | GABRP (0.45) | LMNATSHRGABRPGABRDGABRA1 | |
| SCHEMBL18477468 | 0.75 | FOLH1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9801951-B2 | Drug-conjugates, conjugation methods, and uses thereof | CONCORTIS BIOSYSTEMS, CORP. (US) | 2017-10-31 | — | — | US | disclosed |
| US-20170290925-A1 | Conjugates And Conjugating Reagents | POLYTHERICS LIMITED (GB) | 2017-10-12 | — | — | US | disclosed |
| US-20170035903-A1 | ANTIBODIES, ANTIBODY DRUG CONJUGATES AND METHODS OF USE | EXELIXIS, INC. | 2017-02-09 | — | — | US | disclosed |
| US-20160067350-A1 | Drug-Conjugates, Conjugation Methods, and Uses Thereof | Concortis Biosystems, Corp., a wholly owned Subsidiary of Sorrento Therapeutics, Inc. (US) | 2016-03-10 | — | — | US | disclosed |
| US-20150141646-A1 | Drug-Conjugates, Conjugation Methods, and Uses Thereof | Concortis Biosystems, Corp., a wholly owned subsidary of Sorrento Therapeutics, Inc, (US) | 2015-05-21 | — | — | US | disclosed |
| US-20150105539-A1 | Drug-Conjugates, Conjugation Methods, and Uses Thereof | Concortis Biosystems, Corp., a wholly owned Subsidiary of Sorrento Therapeutics, Inc. (US) | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170035903-A1 | ANTIBODIES, ANTIBODY DRUG CONJUGATES AND METHODS OF USE | GNRHR, FSHR, INHA | ALDH1A1 228/4885LMNA 1629/4885SLC15A2 619/4885 |
| US-20170290925-A1 | Conjugates And Conjugating Reagents | ANPEP, NGLY1, PCTP | ALDH1A1 2594/4885LMNA 2300/4885SLC15A2 3794/4885 |
| US-20160067350-A1 | Drug-Conjugates, Conjugation Methods, and Uses Thereof | PAICS, CES2, DNPEP | ALDH1A1 160/4885LMNA 2439/4885SLC15A2 1251/4885 |
| US-20150141646-A1 | Drug-Conjugates, Conjugation Methods, and Uses Thereof | ABCG2, UGT2B7, UGT1A9 | ALDH1A1 154/4885LMNA 3456/4885SLC15A2 455/4885 |
| US-20150105539-A1 | Drug-Conjugates, Conjugation Methods, and Uses Thereof | PAICS, CES2, DNPEP | ALDH1A1 160/4885LMNA 2439/4885SLC15A2 1251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.