Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL5056227 | 0.87 | — | — | |
| Potassium Ion SCHEMBL8888211 | 0.87 | — | — | |
| Potassium Ion SCHEMBL11612795 | 0.75 | — | — | |
| Potassium Ion SCHEMBL5228448 | 0.75 | — | — | |
| SCHEMBL80 | 0.71 | — | — | |
| Potassium Ion SCHEMBL63086 | 0.71 | — | — | |
| SCHEMBL5398067 | 0.71 | — | — | |
| SCHEMBL5247960 | 0.71 | — | — | |
| Potassium Ion SCHEMBL9450128 | 0.71 | — | — | |
| Hydrogen Sulfide SCHEMBL6248 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240166605-A1 | PROCESS FOR THE PREPARATION OF A PDE4 INHIBITOR | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-05-23 | — | — | US | disclosed |
| US-11981639-B2 | Process for the preparation of a PDE4 inhibitor | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-05-14 | — | — | US | disclosed |
| EP-3587400-B1 | PROCESS FOR THE PREPARATION OF A PDE4 INHIBITOR | CHIESI FARM SPA (IT) | 2024-03-20 | — | — | EP | disclosed |
| US-20220348545-A1 | PROCESS FOR THE PREPARATION OF A PDE4 INHIBITOR | CHIESI FARMACEUTICI S.P.A. (IT) | 2022-11-03 | — | — | US | disclosed |
| EP-4059921-A1 | PROCESS FOR THE PREPARATION OF A PDE4 INHIBITOR | Chiesi Farmaceutici S.p.A. (IT) | 2022-09-21 | — | — | EP | disclosed |
| US-11352327-B2 | Process for the preparation of a PDE4 inhibitor | CHIESI FARMACEUTICI S.P.A. (IT) | 2022-06-07 | — | — | US | disclosed |
| EP-3798209-A1 | PROCESS FOR THE PREPARATION OF A CRYSTAL FORM OF A PDE4 INHIBITOR | Chiesi Farmaceutici S.p.A. (IT) | 2021-03-31 | — | — | EP | disclosed |
| US-20210040040-A1 | PROCESS FOR THE PREPARATION OF A PDE4 INHIBITOR | CHIESI FARMACEUTICI S.P.A. (IT) | 2021-02-11 | — | — | US | disclosed |
| EP-3293176-B1 | CRYSTAL FORM OF A PDE4 INHIBITOR | CHIESI FARM SPA (IT) | 2020-12-02 | — | — | EP | disclosed |
| US-10759761-B2 | Process for the preparation of a PDE4 inhibitor | CHIESI FARMACEUTICI S.P.A. (IT) | 2020-09-01 | — | — | US | disclosed |
| EP-3060551-B1 | PROCESS FOR THE PREPARATION OF A PDE4 INHIBITOR | CHIESI FARM SPA (IT) | 2019-09-18 | — | — | EP | disclosed |
| US-10323003-B2 | Process for the preparation of a PDE4 inhibitor | CHIESI FARMACEUTICI S.P.A. (IT) | 2019-06-18 | — | — | US | disclosed |
| US-20180118686-A1 | PROCESS FOR THE PREPARATION OF A PDE4 INHIBITOR | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-05-03 | — | — | US | disclosed |
| EP-3293176-A1 | CRYSTAL FORM OF A PDE4 INHIBITOR | Chiesi Farmaceutici S.p.a. (IT) | 2018-03-14 | — | — | EP | disclosed |
| US-9890122-B2 | Process for the preparation of a PDE4 inhibitor | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-02-13 | — | — | US | disclosed |
| US-20160326117-A1 | PROCESS FOR THE PREPARATION OF A PDE4 INHIBITOR | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-11-10 | — | — | US | disclosed |
| US-9434691-B2 | Process for the preparation of a PDE4 inhibitor | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-09-06 | — | — | US | disclosed |
| EP-3060551-A1 | PROCESS FOR THE PREPARATION OF A PDE4 INHIBITOR | Chiesi Farmaceutici S.p.A. (IT) | 2016-08-31 | — | — | EP | disclosed |
| WO-2015059050-A1 | PROCESS FOR THE PREPARATION OF A PDE4 INHIBITOR | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-04-30 | — | — | WO | disclosed |
| US-20150111931-A1 | PROCESS FOR THE PREPARATION OF A PDE4 INHIBITOR | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-04-23 | — | — | US | disclosed |