SCHEMBL16655162

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17993476	0.91	ACHE (0.49)	ESR1ESR2ACHELMNASCN2A
	SCHEMBL11863055	0.82	ESR1 (0.57)	ESR1ESR2LMNASCN2AMEN1
	SCHEMBL5579665	0.82	ESR1 (0.83)	ESR1ESR2LMNASCN2AMEN1
	SCHEMBL11305617	0.82	ESR1 (0.57)	ESR1ESR2LMNASCN2AMEN1
	SCHEMBL5846779	0.80	LMNA (0.61)	ESR1ESR2LMNASCN2AS100A4
	SCHEMBL11618288	0.78	MASP2 (0.63)	ESR1ESR2LMNAMEN1KMT2A
	SCHEMBL27420986	0.78	GRIK1 (0.50)	ESR1ESR2ACHELMNAS100A4
	SCHEMBL540147	0.75	ACHE (0.60)	ACHELMNAS100A4TRPV1MEN1
	SCHEMBL11843605	0.75	SCN2A (0.50)	ESR1ESR2LMNASCN2AMEN1
	SCHEMBL5222864	0.74	ESR1 (0.46)	ESR1ESR2LMNASCN2ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.