Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2998516 | 0.80 | TSHR (0.43) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL1313929 | 0.72 | — | — | |
| SCHEMBL1313260 | 0.70 | MEN1 (0.50) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL1314710 | 0.70 | MEN1 (0.50) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL1314042 | 0.70 | MEN1 (0.50) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Butane SCHEMBL22042222 | 0.70 | GABBR2 (0.48) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL10826323 | 0.70 | LMNA (0.38) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL191734 | 0.69 | — | — | |
| SCHEMBL8119186 | 0.69 | CES2 (0.60) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL25174 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9605297-B2 | Method of generating linkage-specific di-and polyprotein probes | UNIVERSITY OF DELAWARE (US) | 2017-03-28 | — | — | US | disclosed |
| US-20160237471-A1 | METHOD OF GENERATING LINKAGE-SPECIFIC DI-AND POLYPROTEIN PROBES | Universtiy of Delaware (US) | 2016-08-18 | — | — | US | disclosed |
| WO-2015057803-A1 | METHOD OF GENERATING LINKAGE-SPECIFIC DI-AND POLYPROTEIN PROBES | ZHUANG ZHIHAO (US) | 2015-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160237471-A1 | METHOD OF GENERATING LINKAGE-SPECIFIC DI-AND POLYPROTEIN PROBES | USP28, USP36, STUB1 | HDAC3 1619/4885HDAC1 1151/4885HDAC2 2302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.