Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634860 | 0.77 | SLC6A4 (0.57) | L3MBTL1SLC6A4SLC6A2KCNH2SLC6A3 | |
| SCHEMBL4027887 | 0.75 | L3MBTL1 (0.57) | L3MBTL1MEN1KMT2AHTR2ASLC6A4 | |
| SCHEMBL1290745 | 0.74 | SLC6A4 (0.42) | L3MBTL1SLC6A4SLC6A2KCNH2SLC6A3 | |
| N,N-Diethylcinnamamide SCHEMBL4956221 | 0.73 | NPC1 (1.00) | NPC1L3MBTL1TRPM8 | |
| N,N-Diethylcinnamamide SCHEMBL4956226 | 0.73 | NPC1 (1.00) | NPC1L3MBTL1TRPM8 | |
| N,N-Diethylcinnamamide SCHEMBL23550023 | 0.73 | NPC1 (1.00) | NPC1L3MBTL1TRPM8 | |
| SCHEMBL803880 | 0.72 | CCR5 (0.54) | L3MBTL1HTR2ASLC6A4SLC6A2KCNH2 | |
| SCHEMBL12693652 | 0.71 | NPC1 (0.72) | NPC1L3MBTL1TRPM8KMT2A | |
| Hydrochloric Acid SCHEMBL5232869 | 0.71 | CCR5 (0.53) | L3MBTL1HTR2ASLC6A4SLC6A2KCNH2 | |
| SCHEMBL22100754 | 0.71 | TRPM8 (0.73) | NPC1L3MBTL1TRPM8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015057963-A1 | FGFR4 INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-23 | — | — | WO | disclosed |