Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601753 | 1.00 | MAPT (0.41) | MAPTMEN1KMT2AEGFRTSHR | |
| SCHEMBL16601752 | 0.80 | FYN (0.42) | MEN1KMT2ATSHRCASP3RAB9A | |
| SCHEMBL16656346 | 0.80 | FYN (0.42) | MEN1KMT2ATSHRCASP3RAB9A | |
| SCHEMBL16601726 | 0.78 | MAPT (0.47) | MAPTMEN1KMT2ANCOA1SMN1; SMN2 | |
| SCHEMBL16656351 | 0.78 | MAPT (0.47) | MAPTMEN1KMT2ANCOA1SMN1; SMN2 | |
| SCHEMBL16656167 | 0.78 | MAPT (0.49) | MAPTMEN1KMT2ATSHRHTT | |
| SCHEMBL6714949 | 0.75 | EGFR (0.60) | EGFRCYP4F2CYP4A11CA1CA2 | |
| SCHEMBL22071077 | 0.72 | SLC6A3 (0.58) | KMT2ACHRM3 | |
| SCHEMBL12577762 | 0.72 | ROCK2 (0.53) | MAPTMEN1KMT2AEGFRSMN1; SMN2 | |
| SCHEMBL16601758 | 0.71 | ALDH1A1 (0.46) | TSHRCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2680077-B1 | Electrophotographic photosensitive member, process catridge, and electrophotographic apparatus | CANON KK (JP) | 2015-10-28 | — | — | EP | disclosed |
| US-9012112-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-04-21 | — | — | US | disclosed |