Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | VHL | P40337 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 2/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601975 | 0.85 | USP7 (0.38) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL13302011 | 0.80 | TDP2 (0.58) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL13302054 | 0.80 | TDP2 (0.45) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL16601977 | 0.79 | USP7 (0.43) | TDP2MAP4K4TGFBR1KMT2AMEN1 | |
| SCHEMBL13302012 | 0.77 | TDP2 (0.42) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL16601733 | 0.72 | TDP2 (0.56) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL16656336 | 0.71 | MAOA (0.41) | GAAKMT2AMEN1THRBBLM | |
| SCHEMBL16656339 | 0.71 | MAPT (0.42) | GAAKMT2AMEN1THRBBLM | |
| SCHEMBL16602054 | 0.70 | TDP2 (0.40) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL16601736 | 0.70 | TDP2 (0.56) | TDP2NSD2ABL1PLCG1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012112-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-04-21 | — | — | US | disclosed |