Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666375 | 0.89 | CYP1A2 (0.37) | CYP1A2PDK1SNCAALDH1A1TSHR | |
| SCHEMBL1665240 | 0.83 | PDK1 (0.40) | CYP1A2PDK1SNCAALDH1A1TSHR | |
| SCHEMBL27485132 | 0.78 | PARP1 (0.37) | CYP1A2PDK1SNCAALDH1A1CYP3A4 | |
| SCHEMBL1665662 | 0.76 | ALOX15 (0.43) | CYP1A2PDK1SNCAALDH1A1TSHR | |
| SCHEMBL888064 | 0.76 | CYP1A2 (0.44) | CYP1A2PDK1SNCAALDH1A1TSHR | |
| SCHEMBL888140 | 0.76 | CYP1A2 (0.40) | CYP1A2PDK1SNCAALDH1A1TSHR | |
| SCHEMBL14676339 | 0.76 | CYP1A2 (0.40) | CYP1A2PDK1SNCAALDH1A1TSHR | |
| SCHEMBL1667872 | 0.76 | ALDH1A1 (0.56) | ALDH1A1TSHRTDP1MEN1RAB9A | |
| SCHEMBL2064927 | 0.75 | FBP1 (0.46) | CYP1A2PDK1SNCATSHRCYP3A4 | |
| SCHEMBL4428319 | 0.75 | CYP1A2 (0.39) | CYP1A2PDK1SNCAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307565-A2 | NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | Lasergen, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009152353-A2 | NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | LASERGEN, INC. (US) | 2009-12-17 | — | — | WO | disclosed |