Pyrophosphoric Acid

Pyrophosphoric Acid

SCHEMBL1665877

CCCCN.O=P(O)(O)OP(=O)(O)O

nearest known ligand 0.56

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 3/20 0.56
GABBR1 Q9UBS5 3/20 0.56
GABRR1 P24046 1/20 0.56
FDPS P14324 3/20 0.48
BLM P54132 3/20 0.48
TDP1 Q9NUW8 1/20 0.48
LPAR3 Q9UBY5 3/20 0.45
LPAR1 Q92633 2/20 0.45
LPAR2 Q9HBW0 2/20 0.45
CYP1A2 P05177 2/20 0.44
TSHR P16473 1/20 0.44
THPO P40225 1/20 0.44
LMNA P02545 2/20 0.43
SMPD1 P17405 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
CYP3A4 P08684 1/20 0.42
NFKB1 P19838 1/20 0.42
PMP22 Q01453 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrophosphoric Acid SCHEMBL3490171 1.00 GABBR2 (0.56) GABBR2GABBR1GABRR1FDPSBLM
Pyrophosphoric Acid SCHEMBL1665875 1.00 GABBR2 (0.56) GABBR2GABBR1GABRR1FDPSBLM
Pyrophosphoric Acid SCHEMBL28346644 0.93 GABBR2 (0.54) GABBR2GABBR1GABRR1FDPSLPAR3
Hexadecylamine SCHEMBL28476428 0.91 DNM1 (0.56) GABBR2GABBR1GABRR1FDPSLPAR3
Hexadecylamine SCHEMBL28476430 0.91 DNM1 (0.56) GABBR2GABBR1GABRR1FDPSLPAR3
Pyrophosphoric Acid SCHEMBL9547111 0.91 DNM1 (0.56) GABBR2GABBR1GABRR1FDPSLPAR3
Pyrophosphoric Acid SCHEMBL9547103 0.91 DNM1 (0.56) GABBR2GABBR1GABRR1FDPSLPAR3
Pyrophosphoric Acid SCHEMBL6261145 0.87 FDPS (0.56) GABBR2GABBR1GABRR1FDPSBLM
Peroxymonophosphate SCHEMBL27906960 0.86 GABBR2 (0.56) GABBR2GABBR1GABRR1FDPSBLM
Pyrophosphoric Acid SCHEMBL14953208 0.86 GABBR2 (0.47) GABBR2GABBR1GABRR1FDPSBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106928269-B Preparation method of phosphate 长春普华制药股份有限公司 2020-03-24 CN claimed
WO-2025264836-A1 METHODS FOR INCREASING SEQUENCING QUALITY OF GC-RICH REGIONS ILLUMINA, INC. (US) 2025-12-26 WO disclosed
WO-2025264831-A1 METHODS FOR INCREASING SEQUENCING QUALITY OF GC-RICH REGIONS ILLUMINA, INC. (US) 2025-12-26 WO disclosed
CN-110590887-B Preparation method of phosphate 江苏金殳医药科技有限公司 2020-12-15 CN disclosed
CN-106928269-B Preparation method of phosphate 长春普华制药股份有限公司 2020-03-24 CN disclosed
CN-110590887-A Preparation method of phosphate 南京帝昌医药科技有限公司 2019-12-20 CN disclosed
CN-110506121-A The cutting reagent of sulfur-bearing hydroxyl and oxidation rinsing agent INTELLIGENT BIO SYSTEMS INC 2019-11-26 CN disclosed
CN-109476694-A Nucleotide analog 奇根科学有限责任公司 2019-03-15 CN disclosed
CN-105705510-B HCV polymerase inhibitors 美迪维尔公司 2018-11-30 CN disclosed
CN-106928269-A A kind of preparation method of phosphate 长春普华制药股份有限公司 2017-07-07 CN disclosed
US-6309836-B1 CONTACTING TARGET NUCLEIC ACID WITH PRIMER SO PRIMER ANNEALS TO NUCLEIC ACID IN SEQUENCE SPECIFIC MANNER, INCORPORATING HYDROCARBYLDITHIOMETHYL-MODIFIED NUCLEOTIDE INTO PRIMER, DETECTING MODIFIED NUCLEOTIDE, IDENTIFYING SEQUENCE OF BASE ILLUMINA, INC. 2001-10-30 US disclosed
WO-2001025247-A1 COMPOUNDS FOR PROTECTING HYDROXYLS AND METHODS FOR THEIR USE QUIATECH AB (SE) 2001-04-12 WO disclosed
EP-0831846-A1 CAPPED SYNTHETIC RNA, ANALOGS, AND APTAMERS Merck & Co., Inc. (US) 1998-04-01 EP disclosed
WO-1998011120-A1 A METHOD OF NUCLEIC ACID SEQUENCING DUKE UNIVERSITY (US) 1998-03-19 WO disclosed
WO-1996041812-A1 OLIGONUCLEOTIDE PHOSPHORYLATION METHOD AND PRODUCTS ISIS INNOVATION LIMITED (GB) 1996-12-27 WO disclosed
WO-1996040159-A1 CAPPED SYNTHETIC RNA, ANALOGS, AND APTAMERS MERCK & CO., INC. (US) 1996-12-19 WO disclosed
WO-1995009248-A1 METHODS AND COMPOSITIONS FOR EFFICIENT NUCLEIC ACID SEQUENCING ARCH DEVELOPMENT CORP. (US) 1995-04-06 WO disclosed
WO-1995006752-A1 A METHOD OF NUCLEIC ACID SEQUENCING DUKE UNIVERSITY (US) 1995-03-09 WO disclosed
WO-1993023416-A1 CHEMICAL SYNTHESIS OF 2',3'-DIDEOXYNUCLEOSIDE 5'-TRIPHOSPHATES UNITED STATES BIOCHEMICAL CORPORATION (US) 1993-11-25 WO disclosed
WO-1993023415-A1 CHEMICAL SYNTHESIS OF 2',3'-DIDEOXYNUCLEOSIDE 5'-(α-THIO) TRIPHOSPHATES UNITED STATES BIOCHEMICAL CORPORATION (US) 1993-11-25 WO disclosed