Pyrophosphoric Acid

Pyrophosphoric Acid

SCHEMBL3490171

CCCCN.CCCCN.CCCCN.O=P(O)(O)OP(=O)(O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 3/20 0.56
GABBR1 Q9UBS5 3/20 0.56
GABRR1 P24046 1/20 0.56
FDPS P14324 3/20 0.48
BLM P54132 3/20 0.48
TDP1 Q9NUW8 1/20 0.48
LPAR3 Q9UBY5 3/20 0.45
LPAR1 Q92633 2/20 0.45
LPAR2 Q9HBW0 2/20 0.45
CYP1A2 P05177 2/20 0.44
TSHR P16473 1/20 0.44
THPO P40225 1/20 0.44
LMNA P02545 2/20 0.43
SMPD1 P17405 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
CYP3A4 P08684 1/20 0.42
NFKB1 P19838 1/20 0.42
PMP22 Q01453 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrophosphoric Acid SCHEMBL1665875 1.00 GABBR2 (0.56) GABBR2GABBR1GABRR1FDPSBLM
Pyrophosphoric Acid SCHEMBL1665877 1.00 GABBR2 (0.56) GABBR2GABBR1GABRR1FDPSBLM
Pyrophosphoric Acid SCHEMBL28346644 0.93 GABBR2 (0.54) GABBR2GABBR1GABRR1FDPSLPAR3
Hexadecylamine SCHEMBL28476428 0.91 DNM1 (0.56) GABBR2GABBR1GABRR1FDPSLPAR3
Hexadecylamine SCHEMBL28476430 0.91 DNM1 (0.56) GABBR2GABBR1GABRR1FDPSLPAR3
Pyrophosphoric Acid SCHEMBL9547111 0.91 DNM1 (0.56) GABBR2GABBR1GABRR1FDPSLPAR3
Pyrophosphoric Acid SCHEMBL9547103 0.91 DNM1 (0.56) GABBR2GABBR1GABRR1FDPSLPAR3
Pyrophosphoric Acid SCHEMBL6261145 0.87 FDPS (0.56) GABBR2GABBR1GABRR1FDPSBLM
Peroxymonophosphate SCHEMBL27906960 0.86 GABBR2 (0.56) GABBR2GABBR1GABRR1FDPSBLM
Pyrophosphoric Acid SCHEMBL14953208 0.86 GABBR2 (0.47) GABBR2GABBR1GABRR1FDPSBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110650968-B Modified nucleosides or nucleotides 深圳华大智造科技股份有限公司 2022-07-05 CN disclosed
CN-110650968-A Modified nucleosides or nucleotides 深圳华大智造科技有限公司 2020-01-03 CN disclosed
US-9657313-B2 Isoprene oligomer, polyisoprene, processes for producing these materials, rubber composition, and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-05-23 US disclosed
US-20170029883-A1 COMPOSITIONS AND METHODS FOR NUCLEOTIDE SEQUENCING ILLUMINA, INC. (US) 2017-02-02 US disclosed
US-9469873-B2 Compositions and methods for nucleotide sequencing ILLUMINA, INC. (US) 2016-10-18 US disclosed
US-20160222418-A1 ISOPRENE OLIGOMER, POLYISOPRENE, PROCESSES FOR PRODUCING THESE MATERIALS, RUBBER COMPOSITION, AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-08-04 US disclosed
US-9371342-B2 Isoprene oligomer, polyisoprene, processes for producing these materials, rubber composition, and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-06-21 US disclosed
US-20150225785-A1 COMPOSITIONS AND METHODS FOR NUCLEOTIDE SEQUENCING ILLUMINA, INC. (US) 2015-08-13 US disclosed
US-9051612-B2 Compositions and methods for nucleotide sequencing ILLUMINA, INC. (US) 2015-06-09 US disclosed
US-20140370498-A1 COMPOSITIONS AND METHODS FOR NUCLEOTIDE SEQUENCING ILLUMINA, INC. (US) 2014-12-18 US disclosed
US-20140171675-A1 ISOPRENE OLIGOMER, POLYISOPRENE, PROCESSES FOR PRODUCING THESE MATERIALS, RUBBER COMPOSITION, AND PNEUMATIC TIRE YAMAGATA UNIVERSITY (JP) 2014-06-19 US disclosed
US-20130244888-A1 COMPOSITIONS AND METHODS FOR NUCLEOTIDE SEQUENCING ILLUMINA, INC. (US) 2013-09-19 US disclosed
EP-2004654-B1 PYRAZOLOPYRIMIDINE DERIVATIVES FOR USE AS KINASE ANTAGONISTS UNIV CALIFORNIA (US) 2013-05-22 EP disclosed
EP-2594597-A1 ISOPRENE OLIGOMER, POLYISOPRENE, PROCESSES FOR PRODUCING THESE MATERIALS, RUBBER COMPOSITION, AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2013-05-22 EP disclosed
US-8399188-B2 Compositions and methods for nucleotide sequencing ILLUMINA, INC. (US) 2013-03-19 US disclosed
US-20100092957-A1 COMPOSITIONS AND METHODS FOR NUCLEOTIDE SEQUENCING ILLUMINA, INC. (US) 2010-04-15 US disclosed
EP-2071927-A2 COMPOSITIONS AND METHODS FOR NUCLEOTIDE SEQUENCING Illumina, Inc. (US) 2009-06-24 EP disclosed
WO-2008042067-A2 COMPOSITIONS AND METHODS FOR NUCLEOTIDE SEQUENCING ILLUMINA, INC. (US) 2008-04-10 WO disclosed
EP-0450060-A1 DNA SEQUENCING SRI INTERNATIONAL (US) 1991-10-09 EP disclosed
WO-1991006678-A1 DNA SEQUENCING SRI INTERNATIONAL (US) 1991-05-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140171675-A1 ISOPRENE OLIGOMER, POLYISOPRENE, PROCESSES FOR PRODUCING THESE MATERIALS, RUBBER COMPOSITION, AND PNEUMATIC TIRE RCE1, GGPS1, TELO2 GABBR2 4707/4885GABBR1 4614/4885GABRR1 4130/4885
US-20160222418-A1 ISOPRENE OLIGOMER, POLYISOPRENE, PROCESSES FOR PRODUCING THESE MATERIALS, RUBBER COMPOSITION, AND PNEUMATIC TIRE RCE1, GGPS1, TELO2 GABBR2 4707/4885GABBR1 4614/4885GABRR1 4130/4885
US-20150225785-A1 COMPOSITIONS AND METHODS FOR NUCLEOTIDE SEQUENCING NT5E, NT5C2, DUT GABBR2 3952/4885GABBR1 4240/4885GABRR1 3413/4885
US-20100092957-A1 COMPOSITIONS AND METHODS FOR NUCLEOTIDE SEQUENCING NT5E, NT5C2, DUT GABBR2 3952/4885GABBR1 4240/4885GABRR1 3413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.