Pyrophosphoric Acid

Pyrophosphoric Acid

SCHEMBL1665875

CCCCN.CCCCN.CCCCN.CCCCN.O=P(O)(O)OP(=O)(O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 3/20 0.56
GABBR1 Q9UBS5 3/20 0.56
GABRR1 P24046 1/20 0.56
FDPS P14324 3/20 0.48
BLM P54132 3/20 0.48
TDP1 Q9NUW8 1/20 0.48
LPAR3 Q9UBY5 3/20 0.45
LPAR1 Q92633 2/20 0.45
LPAR2 Q9HBW0 2/20 0.45
CYP1A2 P05177 2/20 0.44
TSHR P16473 1/20 0.44
THPO P40225 1/20 0.44
LMNA P02545 2/20 0.43
SMPD1 P17405 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
CYP3A4 P08684 1/20 0.42
NFKB1 P19838 1/20 0.42
PMP22 Q01453 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrophosphoric Acid SCHEMBL3490171 1.00 GABBR2 (0.56) GABBR2GABBR1GABRR1FDPSBLM
Pyrophosphoric Acid SCHEMBL1665877 1.00 GABBR2 (0.56) GABBR2GABBR1GABRR1FDPSBLM
Pyrophosphoric Acid SCHEMBL28346644 0.93 GABBR2 (0.54) GABBR2GABBR1GABRR1FDPSLPAR3
Hexadecylamine SCHEMBL28476428 0.91 DNM1 (0.56) GABBR2GABBR1GABRR1FDPSLPAR3
Hexadecylamine SCHEMBL28476430 0.91 DNM1 (0.56) GABBR2GABBR1GABRR1FDPSLPAR3
Pyrophosphoric Acid SCHEMBL9547111 0.91 DNM1 (0.56) GABBR2GABBR1GABRR1FDPSLPAR3
Pyrophosphoric Acid SCHEMBL9547103 0.91 DNM1 (0.56) GABBR2GABBR1GABRR1FDPSLPAR3
Pyrophosphoric Acid SCHEMBL6261145 0.87 FDPS (0.56) GABBR2GABBR1GABRR1FDPSBLM
Peroxymonophosphate SCHEMBL27906960 0.86 GABBR2 (0.56) GABBR2GABBR1GABRR1FDPSBLM
Pyrophosphoric Acid SCHEMBL14953208 0.86 GABBR2 (0.47) GABBR2GABBR1GABRR1FDPSBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025264831-A1 METHODS FOR INCREASING SEQUENCING QUALITY OF GC-RICH REGIONS ILLUMINA, INC. (US) 2025-12-26 WO disclosed
WO-2025264836-A1 METHODS FOR INCREASING SEQUENCING QUALITY OF GC-RICH REGIONS ILLUMINA, INC. (US) 2025-12-26 WO disclosed
EP-3743517-B1 SEQUENCING ADDITIVE QIAGEN SCIENCES LLC (US) 2024-03-06 EP disclosed
US-11821032-B2 DNA sequencing reaction additive IsoPlexis Corporation (US) 2023-11-21 US disclosed
US-20230340583-A1 DNA SEQUENCING REACTION ADDITIVE IsoPlexis Corporation 2023-10-26 US disclosed
US-11548909-B2 Methods of using nucleotide analogues IsoPlexis Corporation (US) 2023-01-10 US disclosed
US-20220315995-A1 THIOL-CONTAINING CLEAVE REAGENTS AND OXIDATIVE WASH QIAGEN WALTHAM, INC. 2022-10-06 US disclosed
US-20220162251-A1 NUCLEOTIDE ANALOGUES QIAGEN SCIENCES, LLC 2022-05-26 US disclosed
US-11117921-B2 Methods for synthesizing nucleotide analogues with disulfide linkers IsoPlexis Corporation (US) 2021-09-14 US disclosed
US-11046726-B2 Nucleotide analogues QIAGEN SCIENCES, LLC (US) 2021-06-29 US disclosed
US-6309836-B1 CONTACTING TARGET NUCLEIC ACID WITH PRIMER SO PRIMER ANNEALS TO NUCLEIC ACID IN SEQUENCE SPECIFIC MANNER, INCORPORATING HYDROCARBYLDITHIOMETHYL-MODIFIED NUCLEOTIDE INTO PRIMER, DETECTING MODIFIED NUCLEOTIDE, IDENTIFYING SEQUENCE OF BASE ILLUMINA, INC. 2001-10-30 US disclosed
WO-2001025247-A1 COMPOUNDS FOR PROTECTING HYDROXYLS AND METHODS FOR THEIR USE QUIATECH AB (SE) 2001-04-12 WO disclosed
EP-0831846-A1 CAPPED SYNTHETIC RNA, ANALOGS, AND APTAMERS Merck & Co., Inc. (US) 1998-04-01 EP disclosed
WO-1998011120-A1 A METHOD OF NUCLEIC ACID SEQUENCING DUKE UNIVERSITY (US) 1998-03-19 WO disclosed
WO-1996041812-A1 OLIGONUCLEOTIDE PHOSPHORYLATION METHOD AND PRODUCTS ISIS INNOVATION LIMITED (GB) 1996-12-27 WO disclosed
WO-1996040159-A1 CAPPED SYNTHETIC RNA, ANALOGS, AND APTAMERS MERCK & CO., INC. (US) 1996-12-19 WO disclosed
WO-1995009248-A1 METHODS AND COMPOSITIONS FOR EFFICIENT NUCLEIC ACID SEQUENCING ARCH DEVELOPMENT CORP. (US) 1995-04-06 WO disclosed
WO-1995006752-A1 A METHOD OF NUCLEIC ACID SEQUENCING DUKE UNIVERSITY (US) 1995-03-09 WO disclosed
WO-1993023415-A1 CHEMICAL SYNTHESIS OF 2',3'-DIDEOXYNUCLEOSIDE 5'-(α-THIO) TRIPHOSPHATES UNITED STATES BIOCHEMICAL CORPORATION (US) 1993-11-25 WO disclosed
WO-1993023416-A1 CHEMICAL SYNTHESIS OF 2',3'-DIDEOXYNUCLEOSIDE 5'-TRIPHOSPHATES UNITED STATES BIOCHEMICAL CORPORATION (US) 1993-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11548909-B2 Methods of using nucleotide analogues NT5C3B, SAMHD1, RNGTT GABBR2 4039/4885GABBR1 4463/4885GABRR1 4340/4885
US-11046726-B2 Nucleotide analogues NT5C3B, SAMHD1, DUT GABBR2 4379/4885GABBR1 4652/4885GABRR1 4657/4885
US-20220162251-A1 NUCLEOTIDE ANALOGUES NT5C3B, SAMHD1, DUT GABBR2 4379/4885GABBR1 4652/4885GABRR1 4657/4885
US-20220315995-A1 THIOL-CONTAINING CLEAVE REAGENTS AND OXIDATIVE WASH SAMHD1, UNG, RNGTT GABBR2 4571/4885GABBR1 4669/4885GABRR1 4706/4885
US-11821032-B2 DNA sequencing reaction additive RNGTT, NSUN2, NT5C3B GABBR2 3755/4885GABBR1 3758/4885GABRR1 4783/4885
US-20230340583-A1 DNA SEQUENCING REACTION ADDITIVE RNGTT, NSUN2, NT5C3B GABBR2 3755/4885GABBR1 3758/4885GABRR1 4783/4885
US-11117921-B2 Methods for synthesizing nucleotide analogues with disulfide linkers RNGTT, NT5C3B, DUT GABBR2 4251/4885GABBR1 4629/4885GABRR1 4340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.