Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18552801 | 0.91 | PTGS2 (0.31) | KDM4EALDH1A1HPGDHTTPTGS2 | |
| SCHEMBL20428777 | 0.90 | PTGS2 (0.33) | KDM4EALDH1A1HPGDHTTMAPT | |
| SCHEMBL16660946 | 0.86 | DGAT1 (0.39) | KDM4EMAPTPTGS2 | |
| SCHEMBL18553038 | 0.85 | PTGS2 (0.30) | PTGS2 | |
| SCHEMBL20428776 | 0.74 | RAB9A (0.37) | KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL18552901 | 0.73 | NR1H2 (0.40) | KDM4EALDH1A1MAPTPTGS2 | |
| SCHEMBL16661275 | 0.72 | PDE10A (0.34) | — | |
| SCHEMBL20428546 | 0.69 | HDAC1 (0.38) | KDM4EALDH1A1HPGDHTT | |
| SCHEMBL16661010 | 0.69 | CA2 (0.32) | MAPT | |
| SCHEMBL20428575 | 0.68 | MEN1 (0.37) | KDM4EALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-A1 | AROMATIC HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2015-04-22 | — | — | EP | disclosed |