Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4290322 | 0.82 | KIF11 (0.33) | RNPEPFOLH1 | |
| SCHEMBL20877707 | 0.78 | RNPEP (0.37) | RNPEPFOLH1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL4956698 | 0.77 | RNPEP (0.62) | RNPEPFOLH1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL17433678 | 0.76 | CA2 (0.37) | MAPK1CA2CHRM1AKR1A1CHRM3 | |
| SCHEMBL474110 | 0.72 | ENPEP (0.35) | ALDH1A1KDM4EALOX15 | |
| SCHEMBL1664400 | 0.72 | RIPK1 (0.31) | MAPK1CA2CHRM1AKR1A1CHRM3 | |
| SCHEMBL3736721 | 0.72 | RNPEP (0.47) | RNPEPFOLH1ALDH1A1TSHRCTSS | |
| SCHEMBL3736726 | 0.72 | RNPEP (0.47) | RNPEPFOLH1ALDH1A1TSHRCTSS | |
| SCHEMBL9463332 | 0.71 | RNPEP (0.56) | RNPEPFOLH1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL8460951 | 0.71 | TSHR (0.32) | TSHRMAPK1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11926857-B2 | Variant LovD polypeptides and their uses | CODEXIS, INC. (US) | 2024-03-12 | — | — | US | disclosed |
| US-20210277432-A1 | VARIANT LOVD POLYPEPTIDES AND THEIR USES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2021-09-09 | — | — | US | disclosed |
| US-11046982-B2 | Variant LovD polypeptides and their uses | CODEXIS, INC. (US) | 2021-06-29 | — | — | US | disclosed |
| US-20200157588-A1 | VARIANT LOVD POLYPEPTIDES AND THEIR USES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2020-05-21 | — | — | US | disclosed |
| US-10590445-B2 | Variant LovD polypeptides and their uses | CODEXIS, INC. (US) | 2020-03-17 | — | — | US | disclosed |
| US-20180187225-A1 | VARIANT LOVD POLYPEPTIDES AND THEIR USES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2018-07-05 | — | — | US | disclosed |
| US-9932616-B2 | Variant LovD polypeptides and their uses | CODEXIS, INC. (US) | 2018-04-03 | — | — | US | disclosed |
| US-20170081685-A1 | VARIANT LOVD POLYPEPTIDES AND THEIR USES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2017-03-23 | — | — | US | disclosed |
| US-9546388-B2 | Variant LovD polypeptides and their uses | CODEXIS, INC. (US) | 2017-01-17 | — | — | US | disclosed |
| US-9181570-B2 | Variant LovD polypeptides and their uses | CODEXIS, INC. (US) | 2015-11-10 | — | — | US | disclosed |
| CN-102574896-B | variant LovD polypeptides and uses thereof | CODEXIS INC | 2015-04-08 | — | — | CN | disclosed |
| US-20150037851-A1 | VARIANT LOVD POLYPEPTIDES AND THEIR USES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2015-02-05 | — | — | US | disclosed |
| EP-2483292-B1 | VARIANT LOVD POLYPEPTIDES AND THEIR USES | CODEXIS INC (US) | 2014-11-12 | — | — | EP | disclosed |
| US-8846362-B2 | Variant LOVD polypeptides and their uses | CODEXIS, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-20130130351-A1 | VARIANT LOVD POLYPEPTIDES AND THEIR USES | CODEXIS, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| US-8383382-B2 | Variant LovD polypeptides and their uses | CODEXIS, INC. (US) | 2013-02-26 | — | — | US | disclosed |
| EP-2483292-A1 | VARIANT LOVD POLYPEPTIDES AND THEIR USES | Codexis, Inc. (US) | 2012-08-08 | — | — | EP | disclosed |
| CN-102574896-A | Variant LovD polypeptides and uses thereof | CODEXIS INC | 2012-07-11 | — | — | CN | disclosed |
| US-20110111468-A1 | VARIANT LOVD POLYPEPTIDES AND THEIR USES | CODEXIS, INC. (US) | 2011-05-12 | — | — | US | disclosed |
| WO-2011041231-A1 | VARIANT LOVD POLYPEPTIDES AND THEIR USES | CODEXIS, INC. (US) | 2011-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10590445-B2 | Variant LovD polypeptides and their uses | LCAT, HMGCR, FNTA | RNPEP 395/4885FOLH1 440/4885ALDH1A1 3660/4885 |
| US-11046982-B2 | Variant LovD polypeptides and their uses | LCAT, HMGCR, FNTA | RNPEP 395/4885FOLH1 440/4885ALDH1A1 3660/4885 |
| US-20210277432-A1 | VARIANT LOVD POLYPEPTIDES AND THEIR USES | LCAT, HMGCR, FNTA | RNPEP 395/4885FOLH1 440/4885ALDH1A1 3660/4885 |
| US-11926857-B2 | Variant LovD polypeptides and their uses | LCAT, HMGCR, FNTA | RNPEP 395/4885FOLH1 440/4885ALDH1A1 3660/4885 |
| US-20200157588-A1 | VARIANT LOVD POLYPEPTIDES AND THEIR USES | LCAT, HMGCR, FNTA | RNPEP 395/4885FOLH1 440/4885ALDH1A1 3660/4885 |
| US-20180187225-A1 | VARIANT LOVD POLYPEPTIDES AND THEIR USES | LCAT, HMGCR, FNTA | RNPEP 395/4885FOLH1 440/4885ALDH1A1 3660/4885 |
| US-20110111468-A1 | VARIANT LOVD POLYPEPTIDES AND THEIR USES | PCSK9, HMGCR, LCAT | RNPEP 338/4885FOLH1 305/4885ALDH1A1 4006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.