Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9939308 | 0.74 | TAAR1 (0.50) | TAAR1HPGDSMN1; SMN2F2NPC1 | |
| SCHEMBL24576508 | 0.73 | PEPD (0.44) | TAAR1ALDH1A1 | |
| SCHEMBL9516971 | 0.73 | EPHX2 (0.62) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL6962946 | 0.70 | ALDH1A1 (0.58) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL15099942 | 0.69 | HPGD (0.44) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11893591 | 0.69 | HPGD (0.44) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11893590 | 0.69 | HPGD (0.44) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL1666286 | 0.68 | SLC6A2 (0.40) | TAAR1HPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL14278969 | 0.68 | TAAR1 (0.42) | TAAR1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24576503 | 0.67 | TAAR1 (0.42) | TAAR1HPGDSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2485728-A1 | WNT PATHWAY ANTAGONISTS | Siena Biotech S.p.a. (IT) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011042145-A1 | WNT PATHWAY ANTAGONISTS | SIENA BIOTECH S.P.A. (IT) | 2011-04-14 | — | — | WO | disclosed |