SCHEMBL16669262

SCHEMBL16669262

[c]1c[c]c2[nH]c3ccccc3c2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
HSD17B10 Q99714 3/20 0.48
GPR3 P46089 2/20 0.48
AHR P35869 2/20 0.42
KDM4E B2RXH2 5/20 0.39
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
LMNA P02545 2/20 0.39
CYP1A2 P05177 2/20 0.39
BLM P54132 2/20 0.39
PARP1 P09874 2/20 0.39
TNKS O95271 1/20 0.39
PMP22 Q01453 1/20 0.39
PARP15 Q460N3 1/20 0.39
TNKS2 Q9H2K2 1/20 0.39
HPGD P15428 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
GLA P06280 1/20 0.38
GAA P10253 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5030 0.74 ALDH1A1 (0.54) ALDH1A1HSD17B10GPR3AHRKDM4E
SCHEMBL698660 0.73 ALDH1A1 (0.48) ALDH1A1HSD17B10GPR3AHRKDM4E
SCHEMBL28458247 0.72 ALDH1A1 (0.52) ALDH1A1HSD17B10GPR3AHRKDM4E
SCHEMBL28379563 0.72 ALDH1A1 (0.52) ALDH1A1HSD17B10GPR3AHRKDM4E
Ammonia Solution, Strong SCHEMBL29143440 0.72 ALDH1A1 (0.52) ALDH1A1HSD17B10GPR3AHRKDM4E
SCHEMBL28756926 0.72 ALDH1A1 (0.52) ALDH1A1HSD17B10GPR3AHRKDM4E
SCHEMBL26678217 0.72 ALDH1A1 (0.52) ALDH1A1HSD17B10GPR3AHRKDM4E
SCHEMBL27478305 0.72 ALDH1A1 (0.46) ALDH1A1HSD17B10GPR3AHRKDM4E
Carbazole SCHEMBL23148507 0.71 ALDH1A1 (0.93) ALDH1A1HSD17B10GPR3AHRKDM4E
Carbazole SCHEMBL29401120 0.71 ALDH1A1 (0.93) ALDH1A1HSD17B10GPR3AHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105794010-B Organic electroluminescent compounds and multi-component host materials and organic electroluminescent devices comprising the same 罗门哈斯电子材料韩国有限公司 2020-12-25 CN disclosed
CN-112110928-A Organic electroluminescent compounds and multi-component host materials and organic electroluminescent devices comprising the same 罗门哈斯电子材料韩国有限公司 2020-12-22 CN disclosed
US-20190189932-A1 TRANSPARENT ELECTRODE AND ELECTRONIC DEVICE Konica Minolta, Inc. (JP) 2019-06-20 US disclosed
US-10153437-B2 Compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-12-11 US disclosed
US-20160336517-A1 Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-11-17 US disclosed
US-20150118507-A1 TRANSPARENT ELECTRODE, ELECTRONIC DEVICE, AND ORGANIC ELECTROLUMINESCENCE ELEMENT Konica Minolta, Inc. (JP) 2015-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10153437-B2 Compound, light-emitting element, light-emitting device, electronic device, and lighting device NR2E3, LEF1, LAGE3 ALDH1A1 332/4885HSD17B10 4303/4885GPR3 2633/4885
US-20160336517-A1 Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device NR2E3, LEF1, LAGE3 ALDH1A1 332/4885HSD17B10 4303/4885GPR3 2633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.