SCHEMBL698660

SCHEMBL698660

[c]1cc(-c2c[c]c3[nH]c4ccccc4c3c2)cc2c1[nH]c1ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
HSD17B10 Q99714 3/20 0.48
GPR3 P46089 2/20 0.48
AHR P35869 1/20 0.47
KIF11 P52732 11/20 0.41
KDM4E B2RXH2 3/20 0.39
LMNA P02545 3/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
TNKS O95271 1/20 0.39
CYP1A2 P05177 1/20 0.39
PARP1 P09874 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
PARP15 Q460N3 1/20 0.39
TNKS2 Q9H2K2 1/20 0.39
HPGD P15428 3/20 0.38
HTT P42858 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1003958 0.95 HSD17B10 (0.43) ALDH1A1HSD17B10GPR3AHRKIF11
SCHEMBL25397447 0.84 KIF11 (0.42) KIF11
SCHEMBL813579 0.82 CDK4 (0.46) KDM4EKMT2AMEN1TNKS2GAA
SCHEMBL11629914 0.79 KIF11 (0.56) ALDH1A1HSD17B10GPR3AHRKIF11
SCHEMBL13387769 0.78 KIF11 (0.58) ALDH1A1HSD17B10GPR3AHRKIF11
SCHEMBL8516198 0.78 KDM4E (0.58) ALDH1A1HSD17B10GPR3AHRKIF11
SCHEMBL20580906 0.76 CTSV (0.54) KIF11KMT2AMEN1PARP1SMN1; SMN2
SCHEMBL20398830 0.76 KIF11 (0.41) ALDH1A1HSD17B10GPR3AHRKIF11
SCHEMBL5030 0.74 ALDH1A1 (0.54) ALDH1A1HSD17B10GPR3AHRKIF11
SCHEMBL16669262 0.73 ALDH1A1 (0.48) ALDH1A1HSD17B10GPR3AHRKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11144876-A None JP disclosed
US-10193077-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2019-01-29 US disclosed
US-20150228912-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-08-13 US disclosed
EP-2423209-B1 BIS-CARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO (JP) 2015-08-05 EP disclosed
US-20150008423-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-01-08 US disclosed
US-8865323-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-10-21 US disclosed
US-8652654-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-02-18 US disclosed
US-20120138912-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2012-06-07 US disclosed
EP-2423209-A1 BIS-CARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Idemitsu Kosan Co., Ltd. (JP) 2012-02-29 EP disclosed
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
JP-H11144876-A LUMINESCENT ELEMENT TORAY IND INC 1999-05-28 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120138912-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME UQCRB, OXA1L, HBS1L ALDH1A1 380/4885HSD17B10 3174/4885GPR3 2959/4885
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same UQCRB, OXA1L, HBS1L ALDH1A1 380/4885HSD17B10 3174/4885GPR3 2959/4885
US-10193077-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same UQCRB, OXA1L, HBS1L ALDH1A1 380/4885HSD17B10 3174/4885GPR3 2959/4885
US-20150228912-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME UQCRB, OXA1L, HBS1L ALDH1A1 380/4885HSD17B10 3174/4885GPR3 2959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.