SCHEMBL1666958

SCHEMBL1666958

O=Cc1c(-c2ccccc2)cc(-c2ccccc2)c(-c2ccccc2)c1C=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
RAB9A P51151 3/20 0.46
LMNA P02545 3/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
PTGS2 P35354 1/20 0.37
BACE1 P56817 1/20 0.37
NPC1 O15118 2/20 0.36
POLB P06746 1/20 0.36
ALDH1A1 P00352 5/20 0.35
CYP2A6 P11509 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
NR1H2 P55055 1/20 0.35
RECQL P46063 1/20 0.35
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1666566 0.90 HPRT1 (0.42) MEN1KMT2ARAB9ALMNAMAPT
SCHEMBL1666662 0.86 MEN1 (0.43) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL547875 0.85 MEN1 (0.41) MEN1KMT2ARAB9ALMNAMAPT
SCHEMBL1669196 0.83 RAB9A (0.40) MEN1KMT2ARAB9ALMNAALDH1A1
SCHEMBL28582026 0.82 MEN1 (0.51) MEN1KMT2ARAB9ALMNAMAPT
SCHEMBL1666377 0.81 ESR2 (0.38) MEN1KMT2ARAB9ALMNAHTT
SCHEMBL548159 0.80 HNF4A (0.46) MEN1KMT2ARAB9AALDH1A1
SCHEMBL1669209 0.80 MEN1 (0.38) MEN1KMT2ARAB9ALMNAALDH1A1
SCHEMBL548482 0.78 LMNA (0.48) MEN1KMT2ARAB9ALMNAMAPT
SCHEMBL28338084 0.78 MEN1 (0.46) MEN1KMT2ARAB9ALMNAPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2808736-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-12-03 EP disclosed
US-8802353-B2 Compound for resist and radiation-sensitive composition specification MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-08-12 US disclosed
EP-2662727-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-11-13 EP disclosed
US-8350096-B2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-01-08 US disclosed
US-20130004896-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION SPECIFICATION ECHIGO MASATOSHI (JP) 2013-01-03 US disclosed
US-20110165516-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION ECHIGO MASATOSHI 2011-07-07 US disclosed
US-7919223-B2 Polyphenol compound synthesized by condensation between aromatic ketone or aldehyde and a phenol; acid-amplified, non-polymeric resist; highly sensitive to KrF excimer lasers, extreme ultraviolet rays, electron beams, X-rays; resist patterns with high resolution, high heat, etch resistance MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2011-04-05 US disclosed
US-20080113294-A1 Compound for Resist and Radiation-Sensitive Composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2008-05-15 US disclosed
EP-1830228-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-09-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110165516-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION XRCC6, XRCC5, KISS1R MEN1 4130/4885KMT2A 103/4885RAB9A 1869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.