SCHEMBL548159

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL548518	0.86	PTPN1 (0.46)	HNF4APTPN1PTPN6AKR1C2AKR1C1
	SCHEMBL547717	0.81	HNF4A (0.45)	HNF4APTPN1PTPN6AKR1C2AKR1C1
	SCHEMBL1666958	0.80	MEN1 (0.46)	MEN1RAB9AKMT2AALDH1A1
	SCHEMBL547875	0.77	MEN1 (0.41)	PTPN1PTPN2MEN1RAB9AKMT2A
	SCHEMBL548758	0.77	ERN1 (0.50)	HNF4APTPN1PTPN6AKR1C2AKR1C1
	SCHEMBL28715775	0.77	PTPN1 (0.55)	HNF4APTPN1PTPN6AKR1C2AKR1C1
	SCHEMBL28410944	0.77	HNF4A (0.53)	HNF4APTPN1PTPN6AKR1C2AKR1C1
	SCHEMBL547148	0.77	HNF4A (0.50)	HNF4AFOLH1FABP3FABP4FABP5
	SCHEMBL29446584	0.77	PTPN1 (0.44)	HNF4APTPN1PTPN6AKR1C2AKR1C1
	SCHEMBL1669196	0.76	RAB9A (0.40)	MEN1RAB9AKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.