Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16670438 | 0.81 | BACE1 (0.40) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL21647668 | 0.72 | HIF1A (0.42) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL1606904 | 0.71 | ALDH1A1 (0.44) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL1607641 | 0.71 | SMN1; SMN2 (0.36) | MAPTALDH1A1KDM4EHPGDSMN1; SMN2 | |
| Ether SCHEMBL28772217 | 0.71 | ALDH1A1 (0.43) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL12476303 | 0.71 | ESR1 (0.47) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL27771050 | 0.70 | HTR1B (0.51) | MAPTALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL8761088 | 0.70 | MAPT (0.66) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL22542329 | 0.70 | NCF1 (0.37) | — | |
| SCHEMBL7861678 | 0.70 | HIF1A (0.55) | MAPTALDH1A1KDM4EHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2861572-B1 | IMPROVED PROCESS FOR THE PREPARATION OF 2-SUBSTITUTED-2-(6-(SUBSTITUTED)-7-METHYLBENZO[D][1,3]DIOXOL-4-YL)ACETIC ACID DERIVATIVES | NATCO PHARMA LTD (IN) | 2018-10-31 | — | — | EP | disclosed |
| US-9227948-B2 | Process for the preparation of 2-substituted-2-(6-(substituted)-7-methylbenzo[D][1,3]dioxol-4-yl)acetic acid derivatives | NATCO PHARMA LIMITED (IN) | 2016-01-05 | — | — | US | disclosed |
| US-20150119587-A1 | PROCESS FOR THE PREPARATION OF 2-SUBSTITUTED-2-(6-(SUBSTITUTED)-7-METHYLBENZO[D][1,3]DIOXOL-4-YL)ACETIC ACID DERIVATIVES | NATCO PHARMA LIMITED (IN) | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119587-A1 | PROCESS FOR THE PREPARATION OF 2-SUBSTITUTED-2-(6-(SUBSTITUTED)-7-METHYLBENZO[D][1,3]DIOXOL-4-YL)ACETIC ACID DERIVATIVES | DERA, XDH, F12 | MAPT 2819/4885ALDH1A1 58/4885KDM4E 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.