Water

Water

SCHEMBL16670332

O.O.O.O.O.O.O=[N+]([O-])[O-].O=[N+]([O-])[O-].O=[N+]([O-])[O-].O=[N+]([O-])[O-].[U+4]

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 known ✓ O00255 1/20 0.67
KMT2A Q03164 1/20 0.67
CA5A P35218 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
TSHR P16473 3/20 0.39
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
HPGD P15428 1/20 0.36
HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL708610 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL27601262 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL10896609 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL2590832 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL10566608 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL708617 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
SCHEMBL561164 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL28398822 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL28478211 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL23854749 0.88 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118895430-B Method for extracting uranium from solution system by using electron beam irradiation technology 烟台大学 2025-03-18 CN claimed
CN-116873858-B Catalyst of radioactive hydrogen storage material, magnesium-based hydrogen storage alloy material and preparation method 烟台大学 2023-12-29 CN claimed
CN-116873858-A Catalyst of radioactive hydrogen storage material, magnesium-based hydrogen storage alloy material and preparation method 烟台大学 2023-10-13 CN claimed
CN-115925031-A Processing method for enriching uranium from water 喀什大学 2023-04-07 CN claimed
CN-119680515-A Adsorption liquid for removing uranium-polluted wastewater and preparation method thereof 常州大学 2025-03-25 CN disclosed
US-12179173-B2 Functionalized porous organic polymers as uranium nano-traps for efficient uranium extraction UNIVERSITY OF SOUTH FLORIDA (US) 2024-12-31 US disclosed
CN-115999516-B Aromatic oxime adsorption material and preparation method and application thereof 东华理工大学 2024-10-15 CN disclosed
CN-118079965-A Preparation method and application of nano black phosphorus/titanium dioxide nano composite material 昆明理工大学 2024-05-28 CN disclosed
US-20240109051-A1 FUNCTIONALIZED POROUS ORGANIC POLYMERS AS URANIUM NANO-TRAPS FOR EFFICIENT URANIUM EXTRACTION UNITED STATES DEPARTMENT OF ENERGY 2024-04-04 US disclosed
CN-116873858-B Catalyst of radioactive hydrogen storage material, magnesium-based hydrogen storage alloy material and preparation method 烟台大学 2023-12-29 CN disclosed
CN-116873858-A Catalyst of radioactive hydrogen storage material, magnesium-based hydrogen storage alloy material and preparation method 烟台大学 2023-10-13 CN disclosed
CN-111867989-B Functionalized porous organic polymers as uranium nanotraps for efficient uranium extraction 南佛罗里达大学 2023-09-26 CN disclosed
CN-115999516-A Aromatic oxime adsorption material and preparation method and application thereof 东华理工大学 2023-04-25 CN disclosed
US-11628419-B2 Functionalized porous organic polymers as uranium nano-traps for efficient uranium extraction UNIVERSITY OF SOUTH FLORIDA (US) 2023-04-18 US disclosed
CN-115925031-A Processing method for enriching uranium from water 喀什大学 2023-04-07 CN disclosed
US-20210162371-A1 FUNCTIONALIZED POROUS ORGANIC POLYMERS AS URANIUM NANO-TRAPS FOR EFFICIENT URANIUM EXTRACTION UNITED STATES DEPARTMENT OF ENERGY 2021-06-03 US disclosed
CN-111867989-A Functionalized porous organic polymers as uranium nanowells for efficient uranium extraction 南佛罗里达大学 2020-10-30 CN disclosed
EP-3664114-A1 USE OF AT LEAST ONE MIXED URANIUM OXIDE AS AN ACTIVE MATERIAL OF A SUPERCAPACITOR ELECTRODE AND SUPERCAPACITOR COMPRISING SUCH AN ACTIVE MATERIAL Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2020-06-10 EP disclosed
WO-2015061013-A1 NUCLEAR FUEL COMPOSITIONS AND METHODS OF MANUFACTURING NUCLEAR FUEL COMPOSITIONS BATTELLE MEMORIAL INSTITUTE (US) 2015-04-30 WO disclosed