Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536717 | 0.93 | MEN1 (0.45) | MEN1KMT2AMAPK1HPGDHTT | |
| SCHEMBL29190820 | 0.85 | HDAC1 (0.41) | MEN1KMT2AMAPK1HPGDHTT | |
| SCHEMBL28678902 | 0.85 | THRA (0.41) | MEN1KMT2AMAPK1NPC1RAB9A | |
| SCHEMBL29253726 | 0.85 | HDAC1 (0.41) | MEN1KMT2AMAPK1HPGDHTT | |
| SCHEMBL2972655 | 0.79 | LMNA (0.50) | MEN1KMT2AMAPK1HPGDHTT | |
| SCHEMBL29202863 | 0.79 | HTR1A (0.39) | MEN1KMT2ATSHRMAPTLMNA | |
| SCHEMBL9781027 | 0.79 | MEN1 (0.45) | MEN1KMT2AMAPK1NPC1RAB9A | |
| SCHEMBL8027233 | 0.77 | IKBKB (0.43) | MEN1KMT2AMAPK1NPC1RAB9A | |
| SCHEMBL17784164 | 0.77 | CYP3A4 (0.34) | HTTTSHRMAPTLMNACYP3A4 | |
| SCHEMBL28882400 | 0.76 | TSHR (0.39) | MEN1KMT2AMAPK1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060589-B9 | LOW MELTING PP HOMOPOLYMER WITH HIGH CONTENT OF REGIOERRORS AND HIGH MOLECULAR WEIGHT | BOREALIS AG (AT) | 2018-04-18 | — | — | EP | disclosed |
| EP-3060589-B1 | LOW MELTING PP HOMOPOLYMER WITH HIGH CONTENT OF REGIOERRORS AND HIGH MOLECULAR WEIGHT | BOREALIS AG (AT) | 2017-12-06 | — | — | EP | disclosed |
| EP-3060589-A1 | LOW MELTING PP HOMOPOLYMER WITH HIGH CONTENT OF REGIOERRORS AND HIGH MOLECULAR WEIGHT | Borealis AG (AT) | 2016-08-31 | — | — | EP | disclosed |
| WO-2015059229-A1 | LOW MELTING PP HOMOPOLYMER WITH HIGH CONTENT OF REGIOERRORS AND HIGH MOLECULAR WEIGHT | BOREALIS AG (AT) | 2015-04-30 | — | — | WO | disclosed |