Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536717 | 0.88 | MEN1 (0.45) | THRATHRBMEN1KMT2AAPAF1 | |
| SCHEMBL16670906 | 0.85 | MEN1 (0.40) | MEN1KMT2AAPAF1RGS12HSP90AA1 | |
| SCHEMBL29253726 | 0.80 | HDAC1 (0.41) | THRATHRBMEN1KMT2AAPAF1 | |
| SCHEMBL29190820 | 0.80 | HDAC1 (0.41) | THRATHRBMEN1KMT2AAPAF1 | |
| SCHEMBL25252028 | 0.79 | THRA (0.40) | THRATHRBMEN1KMT2AAPAF1 | |
| SCHEMBL20185387 | 0.75 | THRA (0.43) | THRATHRBMEN1KMT2AAPAF1 | |
| SCHEMBL28686258 | 0.72 | MEN1 (0.40) | MEN1KMT2AAPAF1RGS12HSP90AA1 | |
| SCHEMBL28351549 | 0.72 | MEN1 (0.45) | MEN1KMT2AAPAF1RGS12HSP90AA1 | |
| SCHEMBL6535320 | 0.70 | LMNA (0.55) | MEN1KMT2AAPAF1RGS12HSP90AA1 | |
| SCHEMBL28371050 | 0.70 | LMNA (0.55) | MEN1KMT2AAPAF1RGS12HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116917309-A | Expression constructs and uses thereof | 斯特兰德生物科技公司 | 2023-10-20 | — | — | CN | claimed |
| CN-116710079-A | Lipid nanoparticles comprising modified nucleotides | 斯特兰德生物科技公司 | 2023-09-05 | — | — | CN | claimed |
| CN-113966221-A | Synthetic oncolytic LNP replicon RNA and use for cancer immunotherapy | 麻省理工学院 | 2022-01-21 | — | — | CN | claimed |
| CN-118338911-A | Human metapneumovirus vaccine | 圣诺菲·帕斯图尔公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-118302154-A | RNA vaccine against infectious diseases | 赫德特生物公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118284410-A | Dried nanoparticle compositions | 赫德特生物公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-118159287-A | Respiratory syncytial virus RNA vaccine | 赛诺菲 | 2024-06-07 | — | — | CN | disclosed |
| CN-116917309-A | Expression constructs and uses thereof | 斯特兰德生物科技公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-116710079-A | Lipid nanoparticles comprising modified nucleotides | 斯特兰德生物科技公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-113966221-A | Synthetic oncolytic LNP replicon RNA and use for cancer immunotherapy | 麻省理工学院 | 2022-01-21 | — | — | CN | disclosed |