SCHEMBL16670956

SCHEMBL16670956

Cc1cc(CBr)cc(C)c1CBr

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
HTR1D P28221 1/20 0.30
HTR1B P28222 1/20 0.30
SKP2 Q13309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL585059 0.80 HRH3 (0.40) ALDH1A1TSHRHTR1DHTR1B
SCHEMBL14211118 0.80 TRPA1 (0.35) TRPA1ALDH1A1TSHRESR1ESR2
SCHEMBL893003 0.80 ALDH1A1 (0.41) ALDH1A1TSHRHTR1DHTR1B
SCHEMBL21749452 0.78 HTR1D (0.41) ALDH1A1HTR1DHTR1B
SCHEMBL17648045 0.78 HRH3 (0.39) ALDH1A1TSHRHTR1DHTR1B
SCHEMBL16637264 0.78 ALDH1A1 (0.33) TRPA1ALDH1A1TSHRESR1ESR2
SCHEMBL11197732 0.77 PYCR1 (0.31)
SCHEMBL11197910 0.77 FFAR4 (0.39) ALDH1A1TSHR
SCHEMBL3436943 0.76 PTGS1 (0.33) TRPA1ALDH1A1TSHRESR1ESR2
SCHEMBL954081 0.76 RAPGEF4 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3060915-A2 DETECTION OF CLEAVAGE ACTIVITY OF AN ENZYME Mologic Limited (GB) 2016-08-31 EP claimed
WO-2015059487-A2 DETECTION OF CLEAVAGE ACTIVITY OF AN ENZYME MOLOGIC LIMITED (GB) 2015-04-30 WO claimed
US-12320804-B2 Detection of cleavage activity of an enzyme MOLOGIC LIMITED (GB) 2025-06-03 US disclosed
US-20250157661-A1 MONITORING INFLAMMATION STATUS MOLOGIC LIMITED (GB) 2025-05-15 US disclosed
US-11953506-B2 Monitoring inflammation status MOLOGIC LIMITED (GB) 2024-04-09 US disclosed
EP-3928100-B1 TREATMENT STRATIFICATION FOR AN EXACERBATION OF INFLAMMATION MOLOGIC LTD (GB) 2023-03-22 EP disclosed
US-20220120760-A1 TREATMENT STRATIFICATION FOR AN EXACERBATION OF INFLAMMATION MOLOGIC LIMITED (GB) 2022-04-21 US disclosed
US-20220120760-A1 TREATMENT STRATIFICATION FOR AN EXACERBATION OF INFLAMMATION MOLOGIC LIMITED (GB) 2022-04-21 US disclosed
EP-3928100-A1 TREATMENT STRATIFICATION FOR AN EXACERBATION OF INFLAMMATION Mologic Limited (GB) 2021-12-29 EP disclosed
US-10866236-B2 Detection of cleavage activity of an enzyme MOLOGIC LIMITED (GB) 2020-12-15 US disclosed
US-10866236-B2 Detection of cleavage activity of an enzyme MOLOGIC LIMITED (GB) 2020-12-15 US disclosed
EP-3060915-B1 DETECTION OF CLEAVAGE ACTIVITY OF AN ENZYME MOLOGIC LTD (GB) 2018-12-05 EP disclosed
US-20170108511-A1 Monitoring Inflammation Status MOLOGIC LIMITED (GB) 2017-04-20 US disclosed
US-20170108511-A1 Monitoring Inflammation Status MOLOGIC LIMITED (GB) 2017-04-20 US disclosed
EP-3111226-A1 MONITORING INFLAMMATION STATUS Mologic Limited (GB) 2017-01-04 EP disclosed
EP-3060915-A2 DETECTION OF CLEAVAGE ACTIVITY OF AN ENZYME Mologic Limited (GB) 2016-08-31 EP disclosed
US-20160238596-A1 Detection of Cleavage Activity Of An Enzyme MOLOGIC LIMITED (GB) 2016-08-18 US disclosed
US-20160238596-A1 Detection of Cleavage Activity Of An Enzyme MOLOGIC LIMITED (GB) 2016-08-18 US disclosed
WO-2015128681-A1 MONITORING INFLAMMATION STATUS MOLOGIC LIMITED (GB) 2015-09-03 WO disclosed
WO-2015059487-A2 DETECTION OF CLEAVAGE ACTIVITY OF AN ENZYME MOLOGIC LIMITED (GB) 2015-04-30 WO disclosed