SCHEMBL1667154

SCHEMBL1667154

CC(=O)C(C(C)=O)c1ccc(C)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 2/20 0.44
ALDH1A1 P00352 6/20 0.44
LMNA P02545 5/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
ACHE P22303 2/20 0.44
ALOX5 P09917 1/20 0.44
TDP1 Q9NUW8 4/20 0.43
SMN1; SMN2 Q16637 4/20 0.42
CHRNA7 P36544 1/20 0.41
PKM P14618 2/20 0.39
HTT P42858 2/20 0.39
ATM Q13315 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
HPGD P15428 1/20 0.39
NLRP1 Q9C000 1/20 0.39
GAA P10253 1/20 0.39
MEN1 O00255 1/20 0.39
NTSR1 P30989 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11458883 0.89 BRD4 (0.44) STAT3ALDH1A1LMNAALOX5NPSR1
SCHEMBL2427033 0.89 SRC (0.48) STAT3ALDH1A1LMNACES2CES1
SCHEMBL19986356 0.83 ALDH1A1 (0.49) STAT3ALDH1A1LMNATDP1SMN1; SMN2
SCHEMBL28464077 0.82 MMP8 (0.50) STAT3ALDH1A1LMNAACHESMN1; SMN2
SCHEMBL28468309 0.82 TGM2 (0.42) STAT3ALDH1A1LMNACES2CES1
SCHEMBL29311540 0.80 TDP1 (0.41) STAT3ALDH1A1LMNAACHEALOX5
SCHEMBL4615333 0.80 ALOX5 (0.53) STAT3ALDH1A1LMNACES2CES1
SCHEMBL1821047 0.80 SRC (0.61) ALDH1A1LMNACES2CES1ACHE
SCHEMBL15447133 0.78 MAPT (0.41) ALDH1A1LMNAACHETDP1SMN1; SMN2
SCHEMBL21269213 0.78 SRC (0.58) ALDH1A1LMNACES2CES1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1830228-B1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2015-08-05 EP disclosed
EP-2808736-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-12-03 EP disclosed
US-8802353-B2 Compound for resist and radiation-sensitive composition specification MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-08-12 US disclosed
EP-2662727-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-11-13 EP disclosed
US-8350096-B2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-01-08 US disclosed
US-20130004896-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION SPECIFICATION ECHIGO MASATOSHI (JP) 2013-01-03 US disclosed
US-20110165516-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION ECHIGO MASATOSHI 2011-07-07 US disclosed
US-7919223-B2 Polyphenol compound synthesized by condensation between aromatic ketone or aldehyde and a phenol; acid-amplified, non-polymeric resist; highly sensitive to KrF excimer lasers, extreme ultraviolet rays, electron beams, X-rays; resist patterns with high resolution, high heat, etch resistance MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2011-04-05 US disclosed
US-20080113294-A1 Compound for Resist and Radiation-Sensitive Composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2008-05-15 US disclosed
EP-1830228-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-09-05 EP disclosed
US-3998872-A PREPARATION OF UNSATURATED CARBONYL COMPOUNDS UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-12-21 US disclosed
US-3936473-A COPPER OR NOBLE METAL SALT, OXYGEN AND ORGANIC ACID CATALYST UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110165516-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION XRCC6, XRCC5, KISS1R STAT3 3310/4885ALDH1A1 1170/4885LMNA 1146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.