SCHEMBL1667191

SCHEMBL1667191

CCN(CC)C(=O)Nc1[c]cccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCC1 P33527 3/20 0.46
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
HSD17B10 Q99714 3/20 0.43
POLB P06746 2/20 0.43
RAB9A P51151 2/20 0.43
LMNA P02545 2/20 0.43
TSHR P16473 1/20 0.43
NPC1 O15118 1/20 0.41
TP53 P04637 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
GAA P10253 1/20 0.41
ALDH1A1 P00352 2/20 0.39
SHMT2 P34897 1/20 0.39
MAOA P21397 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1876681 0.81 TSHR (0.42) TSHRTP53ALDH1A1KMT2A
SCHEMBL5472836 0.78 TSHR (0.33) TSHRKMT2A
SCHEMBL5481191 0.78 MTOR (0.32) TP53KMT2A
SCHEMBL6554139 0.78 ALDH1A1 (0.53) RAB9ALMNATSHRNPC1GAA
SCHEMBL1133942 0.77 MAPT (0.47) POLBRAB9ANPC1SMN1; SMN2GAA
SCHEMBL3761623 0.77 LMNA (0.36) POLBLMNASMN1; SMN2ALDH1A1MEN1
SCHEMBL6294612 0.77 MAPT (0.43) ALDH1A1USP2
SCHEMBL27562668 0.76 CASR (0.36) CA12CA1CA2CA9POLB
SCHEMBL2181642 0.75 TERT (0.49) POLBTSHRSMN1; SMN2GAAALDH1A1
SCHEMBL3126679 0.75 LMNA (0.38) CA12CA1CA2CA9HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10344032-B2 Agents for treating neurogenic inflammation and neuropathic hyperalgesia related disorders PÉCSI TUDOMÁNYEGYETEM (HU) 2019-07-09 US claimed
EP-3194399-B1 NEW AGENTS FOR TREATING NEUROGENIC INFLAMMATION AND NEUROPATHIC HYPERALGESIA RELATED DISORDERS PECSI TUDOMANYEGYETEM (HU) 2019-04-10 EP claimed
EP-3194399-B1 NEW AGENTS FOR TREATING NEUROGENIC INFLAMMATION AND NEUROPATHIC HYPERALGESIA RELATED DISORDERS PECSI TUDOMANYEGYETEM (HU) 2019-04-10 EP disclosed
US-8350995-B2 Optical film, production method of optical film, optically-compensatory film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2013-01-08 US disclosed
US-8147638-B2 Polarizing plate and display using the same KONICA MINOLTA OPTO INC. (JP) 2012-04-03 US disclosed
US-20110155306-A1 POLARIZING PLATE AND DISPLAY USING THE SAME KONICA MINOLTA OPTO, INC. (JP) 2011-06-30 US disclosed
US-7968019-B2 Optical compensation film, method for producing optical compensation film, polarization plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-06-28 US disclosed
US-7922947-B2 Method of producing dispersion FUJIFILM CORPORATION (JP) 2011-04-12 US disclosed
US-7635506-B2 Stretched cellulose ester film, hard coat film, antireflective film, and optical compensation film, and polarizing plate, and display device using them KONICA MINOLTA OPTO, INC. (JP) 2009-12-22 US disclosed
US-20090192256-A1 POLYMER BLEND FILM CONTAINING CYCLIC POLYOLEFIN FUJIFILM CORPORATION (JP) 2009-07-30 US disclosed
US-7541074-B2 Optical film and optical compensatory film, polarizing plate and liquid crystal display using same FUJIFILM CORPORATION (JP) 2009-06-02 US disclosed
US-7153552-B2 Polarizing plate and display KONICA MINOLTA OPTO, INC. (JP) 2006-12-26 US disclosed
US-20060216437-A1 Optical compensation film, method for producing optical compensation film, polarization plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2006-09-28 US disclosed
US-20060182901-A1 Stretched cellulose ester film, hard coat film, antireflective film, and optical compensation film, and polarizing plate, and display device using them KONICA MINOLTA OPTO, INC. (JP) 2006-08-17 US disclosed
US-20060115609-A1 Polarizing plate and display using the same KONICA MINOLTA OPTO, INC. (JP) 2006-06-01 US disclosed
US-20050271834-A1 Cellulose ester film and its manufacturing method, optical film, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. 2005-12-08 US disclosed
US-20050106334-A1 Polarizing plate and display KONICA MINOLTA OPTO, INC. 2005-05-19 US disclosed
US-20050062193-A1 Method of producing dispersion FUJIFILM CORPORATION (JP) 2005-03-24 US disclosed
US-6630973-B1 Compensatory sheet, ellipsoidal polarizing plate and liquid crystal display. FUJI PHOTO FILM CO., LTD. (JP) 2003-10-07 US disclosed
EP-1182470-A1 PHASE CONTRAST PLATE COMPRISING ONE SHEET OF CELLULOSE ESTER FILM CONTAINING AROMATIC COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 2002-02-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10344032-B2 Agents for treating neurogenic inflammation and neuropathic hyperalgesia related disorders TRPV1, P2RX3, P2RX7 ABCC1 716/4885CA12 4832/4885CA1 3483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.