Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15083519 | 0.83 | CA1 (0.42) | TP53CYP51A1CA1CA2CA5A | |
| SCHEMBL23157115 | 0.83 | TP53 (0.42) | ALDH1A1TP53CYP51A1CA1CA2 | |
| SCHEMBL13449655 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TP53CYP51A1CA1CA2 | |
| SCHEMBL8021350 | 0.80 | ALDH1A1 (0.78) | ALDH1A1SLC6A3MEN1KMT2A | |
| SCHEMBL27263883 | 0.79 | ALDH1A1 (0.60) | ALDH1A1SLC6A3MEN1KMT2A | |
| SCHEMBL21671191 | 0.78 | TP53 (0.38) | TP53CYP51A1CA1CA2CA5A | |
| SCHEMBL23623916 | 0.78 | HDAC8 (0.40) | ALDH1A1TP53CYP51A1CA1CA2 | |
| SCHEMBL18074915 | 0.76 | CYP51A1 (0.45) | TP53CYP51A1CA1CA2CA5A | |
| SCHEMBL25303252 | 0.76 | PLAU (0.49) | ALDH1A1 | |
| SCHEMBL23623804 | 0.76 | HDAC8 (0.41) | ALDH1A1TP53SLC6A3HDAC3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252708-A1 | STABILIZED TRIOXACARCIN ANTIBODY DRUG CONJUGATES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-12-16 | — | — | WO | disclosed |
| US-9220794-B2 | Two-photon fluorescent probes for imaging of total sulfide in live cell and tissue, and quantitative estimation of total sulfide concentration using the same | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2015-12-29 | — | — | US | disclosed |
| US-20150118162-A1 | TWO-PHOTON FLUORESCENT PROBES FOR IMAGING OF TOTAL SULFIDE IN LIVE CELL AND TISSUE, AND QUANTITATIVE ESTIMATION OF TOTAL SULFIDE CONCENTRATION USING THE SAME | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150118162-A1 | TWO-PHOTON FLUORESCENT PROBES FOR IMAGING OF TOTAL SULFIDE IN LIVE CELL AND TISSUE, AND QUANTITATIVE ESTIMATION OF TOTAL SULFIDE CONCENTRATION USING THE SAME | CBS, TST, QSOX1 | ALDH1A1 218/4885TP53 3869/4885CYP51A1 3947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.